Search for dissertations about: "Per Thorén"

Showing result 1 - 5 of 7 swedish dissertations containing the words Per Thorén.

  1. 1. Investigating nano-scale viscous and elastic forces withintermodulation : Studies in multifrequency atomic force microscopy

    Author : Per-Anders Thorén; David B. Haviland; Greg Haugstad; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Atomic Force Microscopy; Nonlinear dynamics; Soft materials; High- speed friction measurements; Modeling and numerical simulations; Physics; Fysik;

    Abstract : Investigating visco-elastic forces at the nanometer-scale is important to thecharacterization of soft materials. A quantitative force measurement can be ob-tained using an atomic force microscope (AFM) with a calibrated force transducer(the AFM cantilever). READ MORE

  2. 2. Membrane Interactions of Arginine-Rich Peptides for the Intracellular Delivery of Gene-Targeted Drugs

    Author : Per Thoren; Chalmers University of Technology; []
    Keywords : cellular uptake; translocation; protein transduction; circular dichroism; drug delivery; liposomes; resonance energy transfer; PNA; antigene; antisense;

    Abstract : A major obstacle for the therapeutic use of e.g. oligonucleotides is their inherently poor cellular uptake. A recently discovered class of peptides, denoted cell-penetrating peptides, has been shown to traverse cell membranes, even when conjugated to oligonucleotides or even full-length proteins. READ MORE

  3. 3. Studies of the interaction of penetratin with phospholipid vesicles

    Author : Per Thoren; Daniel Persson; Chalmers University of Technology; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane translocation; vesicle aggregation; cell-penetrating peptides; cellular uptake; Antennapedia homeodomain; circular dichroism; membrane binding; penetratin;

    Abstract : .... READ MORE

  4. 4. The Role of Kit and Thrombopoietin in Regulation of Hematopoietic Stem Cells

    Author : Lina Thorén; Stamcellscentrum (SCC); []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; thrombopoietin; hematopoiesis; Thpo; c-kit; stem cells;

    Abstract : The hematopoietic stem cell (HSC) is postulated to be the ultimate hematopoietic precursor providing production of mature blood cells, and is characterized by a life long capacity for self-renewal and multilineage differentiation. In a healthy human, the HSC produces 1,000,000,000,000 cells per day, illustrating the high turnover within the hematopoietic system and the need for replenishments by HSCs. READ MORE

  5. 5. Cerebral oedema after reperfusion therapy in patients with ischaemic stroke : predictors, outcomes and treatment

    Author : Magnus Thorén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Abstract : Introduction: Reperfusion therapy by intravenous thrombolysis (IVT) and/or endovascular thrombectomy (EVT) are established treatments in ischaemic stroke. Cerebral oedema (COED), caused by dysfunction the blood brain barrier (BBB), is common early after acute ischaemic stroke (AIS), can aggravate the symptoms and worsen the prognosis. READ MORE