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Showing result 1 - 5 of 8 swedish dissertations matching the above criteria.

  2. 1. Two Types of Fibrils in ATTR Amyloidosis : Implications for Clinical Phenotype and Treatment Outcome

    Author : Elisabet Ihse; Per Westermark; Per Hammarström; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amyloid; transthyretin; familial amyloidotic polyneuropathy; TTRV30M; non-TTRV30M; wild-type; liver transplantation; cardiomyopathy; fibril composition; Biokemi; Biochemistry; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi; Experimentell patologi; Experimental Pathology; Medical Biochemistry; Medicinsk biokemi; Molecular Biology; Molekylärbiologi; Pathology; Patologi;

    Abstract : Systemic amyloidoses are a group of lethal diseases where proteins aggregate into fibrillar structures, called amyloid fibrils, that deposits throughout the body. Transthyretin (TTR) causes one type of amyloidosis, in which the aggregates mainly infiltrate nervous and cardiac tissue. READ MORE

  4. 2. Power to gas : Bridging renewable electricity to the transport sector

    Author : Farzad Mohseni; Per Alvfors; Mats Westermark; Lars Pettersson; Maria Grahn; Björn Frostell; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; transport; renewable electricity; synthetic fuels; energy; power to gas;

    Abstract : Globally, transport accounts for a significant part of the total energy utilization and is heavily dominated by fossil fuels. The main challenge is how the greenhouse gas emissions in road transport can be addressed. Moreover, the use of fossil fuels in road transport makes most countries or regions dependent on those with oil and/or gas assets. READ MORE

  5. 3. Apolipoprotein A-IV and Transthyretin in Swedish Forms of Systemic Amyloidosis

    Author : Joakim Bergström; Per Westermark; Giampaolo Merlini; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pathology; Amyloid; Fibril; Aggregation; Apolipoprotein A-IV; Transthyretin; Seeding; Senile systemic amyloidosis; Familial amyloidotic polyneuropathy; Patologi; Pathology; Patologi;

    Abstract : Over 20 different plasma proteins have been shown to have the capacity to undergo conformational changes and self-assemble into highly stable and insoluble amyloid fibrils. One, transthyretin (TTR), consists of 127 amino acid residues arranged in eight β-strands (named A to H) and is involved in two different clinical forms of amyloidosis. READ MORE

  6. 4. Novel cycles using carbon dioxide as working fluid : new ways to utilize energy from low-grade heat sources

    Author : Yang Chen; Per Gunnar Lundqvist; Mats Westermark; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Thermal energy engineering; Termisk energiteknik;

    Abstract : This licentiate thesis proposes and analyzes three carbon dioxide novel cycles, namely: the carbon dioxide transcritical power cycle, the carbon dioxide Brayton cycle and the carbon dioxide cooling and power combined cycle. Due to the different characteristics of each cycle, the three cycles are suitable for different applications. READ MORE

  7. 5. Influence of Genes and Post-translational Modifications in the Pathogenesis of Light Chain Amyloidosis

    Author : Stina Enqvist; Per Westermark; Robert Kisilevsky; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN; Medicine; medicin;

    Abstract : Amyloid is formed when a normally soluble protein undergoes conformational changes that results in self-aggregation. The pathogenic protein in light chain amyloidosis is an immunoglobulin light chain produced by a plasma cell clone mainly in the bone marrow. READ MORE