Search for dissertations about: "Periplasmic binding protein"

Showing result 16 - 19 of 19 swedish dissertations containing the words Periplasmic binding protein.

  2. 16. Combinatorial Synthesis of Pilicides

    Author : Anette Svensson; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; gel-phase 19F NMR spectroscopy; fluorinated linkers; E. coli bacteria; pilicides; combinatorial chemistry; solid-phase synthesis; Organic chemistry; Organisk kemi;

    Abstract : This thesis describes a combinatorial approach to design and synthesis of three libraries of compounds, referred to as pilicides, designed to target periplasmic chaperones present in uropathogenic Escherichia coli bacteria that are the main cause of urinary tract infections. Periplasmic chaperones are required for assembly of adhesive organelles, i. READ MORE

  4. 17. Structural basis of cysteine biosynthesis and peptidoglycan remodelling in Mycobacterium tuberculosis

    Author : Dominic Böth; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mycobacterium tuberculosis is the causative agent of tuberculosis, which is responsible for 1.3 million deaths annually. Treatment is difficult due to an elaborate defense machinery, which includes specific metabolic changes of the bacilli upon exposure to antibiotics and the immune response of the host. READ MORE

  5. 18. Assembly and adhesive properties of curli : a stationary phase-specific surface organelle in Gram-negative enteric bacteria

    Author : Mårten Hammar; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Escherichia colilcurli fimbriae csgstarvation;

    Abstract : The natural environments of bacteria are most often characterized by suboptimal conditions for growth, e. g., limited supply of nutrients. Consequently, periods of dormancy or negligible growth are the rule rather than the exception. READ MORE

  6. 19. Outer membrane vesicle-mediated export of virulence factors from Gram-negative bacteria

    Author : Pramod Kumar Rompikuntal; Sun Nyunt Wai; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Outer membrane vesicles; CDT; PGN; PrtV; Campylobacter jejuni; Vibrio cholerae; Aggregatibacter actinomycetemcomitans; molekylärbiologi; Molecular Biology;

    Abstract : The Gram-negative, motile bacterium Campylobacter jejuni is a causative agent of food-borne gastroenteritis. Cytolethal distending toxin (CDT) is one of the important virulence factors for C. jejuni pathogenesis. It was not previously known how CDT is released from C. READ MORE