Search for dissertations about: "Peter Brzezinski"

Showing result 11 - 15 of 22 swedish dissertations containing the words Peter Brzezinski.

  1. 11. Cytochrome c Oxidase dysfunction in cancer : Exploring the molecular mechanisms

    Author : Ida Namslauer; Peter Brzezinski; Susanne Arnold; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : Mutations in genes encoding the mitochondrial enzyme Cytochrome c Oxidase (CytcO) have lately been found in connection to various types of cancer. Some mutations result in substitutions of highly conserved amino-acid residues. READ MORE

  2. 12. Protein and lipid interactions within the respiratory chain : Studies using membrane-mimetic systems

    Author : Tobias Nilsson; Peter Brzezinski; Petra Hellwig; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Cytochrome c oxidase; ATP synthase; Bioenergetics; membrane-mimetics; Rcf1; liposomes; oxidative phosphorylation; lipids; protein-protein interactions; Biochemistry; biokemi;

    Abstract : Energy conversion from nutrients to ATP is a vital process in cells. The process, called oxidative phosphorylation (OXPHOS) is performed by a combination of membrane-bound proteins. These proteins have been studied in great detail in the past, however much is still unknown about how they interact with each other. READ MORE

  3. 13. Membrane-mimetic systems : Novel methods and results from studies of respiratory enzymes

    Author : Gustav Nordlund; Peter Brzezinski; Joachim Heberle; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Lipids; membrane proteins; method development; respiration; reconstitution; supported membranes; SNAREs; liposome fusion; lipid-protein interactions; Biochemistry; biokemi;

    Abstract : The processes localized to biological membranes are of great interest, both from a scientific and pharmaceutical point of view. Understanding aspects such as the detailed mechanism and regulation of these processes requires investigation of the structure and function of the membrane-bound proteins in which they take place. READ MORE

  4. 14. Membrane effects on proton transfer in cytochrome c oxidase

    Author : Linda Näsvik Öjemyr; Peter Brzezinski; Anthony G. Lee; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytochrom c oxidase; lipids; membrane; proton transfer; Biochemistry; biokemi;

    Abstract : The biological membrane is composed of lipids and proteins that make up dynamic barriers around cells and organelles. Membrane-spanning proteins are involved in many key processes in the cell such as energy conversion, nerve conduction and signal transduction. READ MORE

  5. 15. Proton transfer in nitric oxide reducing heme-copper oxidases

    Author : Joachim Reimann; Pia Ädelroth; Peter Brzezinski; Michael Wilson; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; heme-copper oxidases; nitric oxide; proton transfer; electron transfer; proton-transfer pathway; Biochemistry; biokemi;

    Abstract : Heme-copper oxidases (HCuOs) are best known as terminal oxidases in the aerobic respiratory chain, in which they catalyze the reduction of oxygen to water. By receiving protons and electrons from opposite sides of the membrane as well as pumping protons, HCuOs contribute to the electrochemical proton gradient over the membrane that can be used for ATP synthesis. READ MORE