Search for dissertations about: "Peter Brzezinski"

Showing result 16 - 20 of 22 swedish dissertations containing the words Peter Brzezinski.

  1. 16. Modulators of Saccharomyces cerevisiae cytochrome c oxidase : Implications for the regulation of mitochondrial respiration

    Author : Camilla Rydström Lundin; Peter Brzezinski; Christoph von Ballmoos; Shelagh Ferguson-Miller; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; cytochrome c; OXPHOS; membrane protein; kinetics; ligand-binding; electron transfer; Rcf1; respiratory supercomplexes; Saccharomyces cerevisiae; Biochemistry; biokemi;

    Abstract : Oxidative phosphorylation in mitochondria is performed by enzyme complexes and electron carriers that reside in the inner membrane. It is now generally accepted that these respiratory enzyme complexes assemble into larger so-called supercomplexes. However, it is presently not known why, under which conditions or how these supercomplexes form. READ MORE

  2. 17. Proton, Electron, and O2 transfer in Cytochrome c Oxidase

    Author : Lina Salomonsson; Peter Brzezinski; Marilyn Gunner; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytochrome c oxidase; electron transfer; proton transfer; proton pumping; kinetic isotope effect; Biochemistry; Biokemi;

    Abstract : In mitochondria and aerobic bacteria energy conservation involves electron transfer through the membrane-bound protein of the respiratory chain to oxygen. Cytochrome c oxidase (CcO) catalyzes the reduction of oxygen to water. Part of the energy released in this reaction is used to pump protons across the membrane. READ MORE

  3. 18. Wiring Components of the Respiratory Chain : Modulation of the Respiratory Chain in Yeast and Bacteria

    Author : Jacob Schäfer; Peter Brzezinski; Dennis Winge; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cytochrome c oxidase; Electron transfer; Membrane protein; Ligand; Kinetics; Mechanism; Rcf1; Cytochrome c; Respiratory supercomplex; Cryo-electron microscopy; Biochemistry; biokemi;

    Abstract : The enzyme complexes of the respiratory chain are organized in supramolecular assemblies, so-called respiratory supercomplexes. In the yeast Saccharomyces cerevisiae, these supercomplexes consist of two copies of complex III (bc1 complex) and one or two copies of complex IV (cytochrome c oxidase, CytcO). READ MORE

  4. 19. Molecular machinery of a membrane-bound proton pump : Studies of charge transfer reactions in cytochrome c oxidase

    Author : Emelie Svahn; Peter Brzezinski; Ville Kaila; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein; respiration; redox reaction; cytochrome aa3; cytochrome c oxidase; Biochemistry; biokemi;

    Abstract : In cellular respiration, electron transfer from the breakdown of foodstuff is coupled to the formation of an electrochemical proton gradient. This is accomplished through proton translocation by respiratory complexes, and the proton gradient is subsequently used e.g. to drive ATP production. READ MORE

  5. 20. Establishing the molecular mechanism of sodium/proton exchangers

    Author : Povilas Uzdavinys; David Drew; Peter Brzezinski; M.D. Daniel Fuster; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; membrane protein; secondary active transporters; sodium proton exchangers; proton transport; structure; energetics; Biochemistry; biokemi;

    Abstract : Sodium/proton exchangers are ubiquitous secondary active transporters that can be found in all kingdoms of life. These proteins facilitate the transport of protons in exchange for sodium ions to help regulate internal pH, sodium levels, and cell volume. READ MORE