Search for dissertations about: "Peter Brzezinski"
Showing result 6 - 10 of 22 swedish dissertations containing the words Peter Brzezinski.
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6. Adaptive Responses by Transcriptional Regulators to small molecules in Prokaryotes : Structural studies of two bacterial one-component signal transduction systems DntR and HpNikR
Abstract : Prokaryotes are continually exposed to variations in their environment. Survival in unstable milieu requires a wide range of transcriptional regulators (TRs) that respond to specific environmental and cellular signals by modulating gene expression and provide an appropriate physiological response to external stimuli. READ MORE
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7. Structural elements involved in protein-mediated proton transfer : Implications from studies of cytochrome c oxidase
Abstract : Proton transfer is one of the most common reactions in biological systems. During energy conversion inside a cell, proton transfer is crucial to maintain an electrochemical proton gradient across the cell membrane. This gradient is in turn used to e.g. READ MORE
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8. Experimental studies of proton translocation reactions in biological systems : Electrogenic events in heme-copper oxidases
Abstract : Terminal heme-copper oxidases (HCuOs) are transmembrane proteins that catalyze the final step in the respiratory chain - the reduction of O2 to H2O, coupled to energy conservation by generation of an electrochemical proton gradient. The most extensively investigated of the HCuOs are the aa3-type oxidases, to which cytochrome c oxidase (CytcO) belongs, which uses energy released in the O2-reduction for proton pumping. READ MORE
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9. In search of a biosensor for DNT detection : Studies of inducer response and specificity of DntR
Abstract : The primary aim of the work presented in this thesis was to change the inducer specificity of the DntR protein in order to improve the response to DNT. The long-term goal is to use this protein in a biosensor for DNT, a signature compound for detection of the explosive TNT. READ MORE
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10. Role of respiratory supercomplexes : Electronic connection between complexes III and IV
Abstract : In the final step of cellular respiration, electrons are transferred through the respiratory chain to reduce molecular oxygen to water. The energy released in this chain is used to maintain a proton electrochemical gradient across the cell membrane, which is used, for example, by the ATP synthase to produce ATP. READ MORE