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Showing result 1 - 5 of 12 swedish dissertations matching the above criteria.
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1. Insulin Signaling in Human Adipocytes a Systems Biology Approach
Abstract : Obesity and a sedentary life style are associated with type 2 diabetes, a disease starting with insulin resistance in the adipose tissue, which spreads to the whole body. Despite large research efforts to understand the insulin signaling system, there is little knowledge of the mechanisms behind insulin resistance and type 2 diabetes developments. READ MORE
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2. A molecular approach to insulin signalling and caveolae in primary adipocytes
Abstract : The prevalence of type II diabetes is increasing at an alarming rate due to the western world lifestyle. Type II diabetes is characterized by an insulin resistance distinguished by impaired glucose uptake in adipose and muscle tissues. READ MORE
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3. Expanding role of caveolae in control of adipocyte metabolism : proteomics of caveolae
Abstract : The primary function of adipose tissue is to store energy in the form of triacylglycerol, which is hydrolyzed to fatty acids to supply other tissues with energy. While insulin promotes the storage of triacylglycerol, catecholamines stimulate its hydrolysis. READ MORE
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4. Insulin signaling in primary adipocytes in insulin sensitive and insulin resistant states
Abstract : Increasing numbers of people world-wide develops the disease type 2 diabetes. Development of type 2 diabetes is characterized by a shift from an insulin sensitive state to an insulin resistant state in peripheral insulin responding organs, which originates from the development of insulin resistance in the adipose tissue. READ MORE
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5. Insulin signalling in human adipocytes : mechanisms of insulin resistance in type 2 diabetes
Abstract : Prevalensen av fetma ökar drastiskt i stora delar av världen och utgör en stor riskfaktor för att utveckla insulinresistens och typ 2 diabetes. Fettväven kan bli mycket stor om för mycket energi tas upp av kroppen. READ MORE