Search for dissertations about: "Pharmaceutical Physical Chemistry"

Showing result 16 - 20 of 63 swedish dissertations containing the words Pharmaceutical Physical Chemistry.

  2. 16. Mass Transport through Phase Separated Films - Effects of Ethyl Cellulose Molecular Weight on Cellulose Derivative Blends for Pharmaceutical Coatings

    Author : Helene Andersson; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Coating; Ethyl cellulose; Diffusion; Mass transport; Solvent evaporation; Molecular weight; Phase separation; Film; Hydroxypropyl cellulose; Polymer blend; Cellulose derivatives; Controlled release;

    Abstract : Polymer blends are utilized for a variety of applications, not least in pharmaceutical coatings for controlled release of drugs. For instance, blends of ethyl cellulose (EC) and the water-soluble hydroxypropyl cellulose (HPC) can be used to coat drug pellets for oral extendedrelease formulations. READ MORE

  4. 17. On Phase Behaviours in Lipid/Polymer/Solvent/Water Systems and their Application for Formation of Lipid/Polymer Composite Particles

    Author : Anna Imberg; Per Hansson; Krister Thuresson; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Biodegradable; CLSM; Composite Particles; Controlled Release; Cubic Phases; Drug Delivery; Flory-Huggins Theory; FT-PGSE-NMR; IPMS; Liquid Phase; Lipid Domains; Liquid Handler; Microspheres; Microstructure; Phase Behaviour; Phase Separation; Polymer Matrix; SAXS; Segregation; Sponge Phase; Swelling; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

    Abstract : A new kind of lipid/polymer composite particle, consisting of a biodegradable polymer matrix with well-defined lipid domains, has been created. The lipid used is the water-swelling lipid monoolein (MO), which forms a reversed bicontinuous cubic diamond structure in aqueous solutions. READ MORE

  5. 18. Characterisation of Aqueous Solutions, Liquid Crystals and Solid State of Non-ionic Polymers in Association with Amphiphiles and Drugs

    Author : Annika Ridell; Martin Malmsten; Sven Engström; David Attwood; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; polymer; surfactant; phase diagram; x-ray diffraction; fluorescence spectroscopy; calorimetry; PEG; cellulose ether; viscometry; cubic phase; liquid crystals; drugs; solid dispersion; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

    Abstract : Cellulose ethers and polyethylene glycols are used in drug formulations as water swelling or water soluble matrices. Polar lipids, for example monoglycerides, and surfactants can be used to solubilise hydrophobic or amphiphilic drugs and to formulate potential drug delivery vehicles such as emulsions, liposomes and cubic phases. READ MORE

  6. 19. Phase Transformations in Solid Pharmaceutical Materials Studied by AFM, ESCA, DSC and SAXS

    Author : Denny Mahlin; Göran Alderborn; Sven Engström; Duncan Q M Craig; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; polymer; lipid; lactose; phase transformation; phase formation; crystallisation; AFM; X-ray diffraction; ESCA; DSC; solid dispersion; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi;

    Abstract : Mixing excipients is a common way to produce pharmaceutical materials with suitable properties for drug formulation. An understanding of the basic mechanisms involved in the formation and transformation of the structures of solid state mixtures is crucial if one is to be able to produce materials with the desired properties in a reliable way. READ MORE

  7. 20. FACING THE CHALLENGE OF SKIN PENETRATION - A STUDY ON LIPIDIC LIQUID CRYSTALLINE PHASES FOR DERMAL DRUG DELIVERY

    Author : Hanne Evenbratt; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; 5-diol; liquid crystalline phases; N-Methyl-2-pyrrolidone; pentane-1; glyceryl monooleat; propylene glycol; dermal drug delivery; glyceryl monooleyl ether; cubic phase; reversed hexagonal phase;

    Abstract : The skin is a barrier which protects us against daily attacks of foreign substances. From a pharmaceutical perspective it is also an interesting delivery route with its large surface and possibility to reach the blood stream circumventing first passage metabolism. With the varied size, structure etc. READ MORE