Search for dissertations about: "Pharmaceutical Physical Chemistry"

Showing result 6 - 10 of 63 swedish dissertations containing the words Pharmaceutical Physical Chemistry.

  2. 6. Heterogeneities in polymer gels: Effects on swelling and mechanical properties

    Author : Mikael Larsson; Chalmers tekniska högskola; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gel; Phase separation; Heterogeneities; Polyacrylic acid.; HPMC; Glass transition temperature; Microfibrillated cellulose; Filler; Elastomer;

    Abstract : Polymeric hydrogels is a class of scientifically interesting materials that are being extensively studied. They are found in numerous applications within; drug delivery, hygiene products, food industry, analytical chemistry, etc. In addition, polymeric hydrogels have promising future applications as; cell scaffolds, implants, sensors, etc. READ MORE

  4. 7. Structure evolution of phase-separated EC/HPC films for controlled drug release

    Author : Pierre Carmona; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; electron microscopy; coarsening; cellulose; phase separation kinetics; drug delivery; phase separation mechanisms; porous film; biopolymer; controlled drug release; confocal laser scanning microscope; spin-coating.;

    Abstract : Porous phase-separated ethylcellulose/hydroxypropylcellulose (EC/HPC) films are used to control drug transport out of pharmaceutical pellets. The drug transport rate is determined by the structure of the porous films that are formed as the water-soluble HPC leaches out. READ MORE

  5. 8. Crystallization of Parabens : Thermodynamics, Nucleation and Processing

    Author : Yang Huaiyu; Åke Rasmuson; Joop ter Horst; KTH; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Nucleation; Induction time; Interfacial energy; Ethyl paraben; Propyl paraben; Butyl paraben; Methanol; Ethanol; Propanol; Acetone; Ethyl acetate; Solubility; Thermodynamics; Activity; Activity coefficient; Liquid-liquid phase separation; Ternary phase diagram; Melting point; Boiling point; Polarity; Cooling crystallization; Sandwich crystal; Porous; Particle Vision and Measurement; Focused Beam Reflectance Method; Infrared Spectroscopy; Confocal Raman Microscopy; X-Ray Diffraction; Differential Scanning Calorimetry; SRA - E-Science SeRC ; SRA - E-vetenskap SeRC ;

    Abstract : In this work, the solubility of butyl paraben in 7 pure solvents and in 5 different ethanol-water mixtures has been determined from 1 ˚C to 50 ˚C. The solubility of ethyl paraben and propyl paraben in various solvents has been determined at 10 ˚C. READ MORE

  6. 9. Drugs and polymers in dissolving solid dispersions : NMR imaging and spectroscopy

    Author : Carina Dahlberg; István Furó; Anna Millqvist-Fureby; Michael Schuleit; Jadwiga Tritt-Goc; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physical chemistry; Fysikalisk kemi; Surface and colloid chemistry; Yt- och kolloidkemi; PHARMACY; FARMACI;

    Abstract : The number of poorly water-soluble drug substances in the pharmaceutical pipeline is increasing, and thereby also the need to design effective drug delivery systems providing high bioavailability. One favourable formulation approach is preparation of solid dispersions, where dispersing a poorly water-soluble drug in a water-soluble polymer matrix improves the dissolution behaviour and the bioavailability of the drug. READ MORE

  7. 10. Phase Phenomena in Polymer Networks : Empirical Studies on the Influence of Hydrophobicity, Charge Density and Crosslinks on Macroion-Induced Phase Transitions in Polyelectrolyte Gels

    Author : Martin Andersson; Per Hansson; Lennart Piculell; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Gel; microgel; microsphere; polystyrenesulfonate; polyacrylate; polyacrylicacid; DoTAB; DoTAC; CTAB; CTAC; network; polyelectrolyte; complex salt; self assembly; phase behaviour; hysteresis; thermodynamic; core-shell; lysozyme; cytochrome c; microscopy; micromanipulator; elastomer; elastic; protein; surfactant; phase behaviour; sorting; PHARMACY; FARMACI; Physical chemistry; Fysikalisk kemi;

    Abstract : The thesis concerns polyelectrolyte gels in contact with oppositely charged proteins and surfactant micelles, and includes of four papers (I-IV). In paper I confocal Raman spectroscopy was introduced as a method to trace micelles and investigate the structure of gel-surfactant complexes, in phase separated gel spheres. READ MORE