Search for dissertations about: "Pharmaceutics"

Showing result 6 - 10 of 66 swedish dissertations containing the word Pharmaceutics.

  2. 6. Prolonged Drug Release from Gels, using Catanionic Mixtures

    Author : Tobias Bramer; Katarina Edsman; Per Hansson; Stefan Ulvenlund; Uppsala universitet; []
    Keywords : Pharmaceutics; gel; catanionic; vesicle; micelle; controlled release; diffusion; surfactant; drug delivery; Galenisk farmaci;

    Abstract : The use of catanionic drug-surfactant mixtures was proven to be an efficient novel method of obtaining prolonged drug release from gels. It was shown that various commonly used drug compounds are able to form catanionic mixtures together with oppositely charged surfactants. READ MORE

  4. 7. New Concepts in Administration of Drugs in Tablet Form : Formulation and Evaluation of a Sublingual Tablet for Rapid Absorption, and Presentation of an Individualised Dose Administration System

    Author : Susanne Bredenberg; Christer Nyström; Carla Caramella; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Interactive mixture; Dose homogeneity; Disintegration; Bioadhesion; Oromucosal delivery; Sublingual tablet; Rapid absorption; Individual dosage; Drug dispensing device; Galenisk farmaci; Pharmaceutics; Galenisk farmaci; galenisk farmaci; Pharmaceutics;

    Abstract : This thesis presents two new concepts in oral drug administration and the results of evaluation of some relevant formulation factors.Investigation into improving the homogeneity of mixtures for tableting indicated that it may be possible to obtain interactive dry mixtures of micronised drugs containing drug proportions as low as 0.015% w/w. READ MORE

  5. 8. Discovery of N-hydroxyguanidines as novel electron acceptors of xanthine oxidase : Potential new drugs for treatment of ischemia and reperfusion injury

    Author : Maija Dambrova; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; xanthine oxidase; N-hydroxyguanidine derivatives; ischemia and reperfusion; reduction; inhibition; superoxide; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; galenisk farmaci; Pharmaceutics;

    Abstract : Xanthine oxidase (EC 1.1.3.22) is one of the major enzymatic sources of oxygen-derived free radicals. READ MORE

  6. 9. Catanionic Aggregates in Gels : Prolonged Drug Release and Potential Implications for Topical Use

    Author : Noel Dew; Erik Björk; Stefan Ulvenlund; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Galenisk farmaci; Galenisk farmaci; Pharmaceutics;

    Abstract : Gels are popular dosage forms.  This topical dosage form may be advantageous compared to oral or parenteral dosage forms. Favorable rheological or bioadhesive properties of gels might provide extended contact times at the site of administration compared to aqueous solutions. READ MORE

  7. 10. Spray-Dried Powders for Inhalation : Particle Formation and Formulation Concepts

    Author : Jessica Elversson; Göran Alderborn; Anna Millqvist-Fureby; Lars Hovgaard; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutics; Spray drying; Particle formation; Density; Protein formulation; Encapsulation; Coating; Competitive adsorption; Polymer; ESCA; AFM; FTIR; Galenisk farmaci; Pharmaceutics; Galenisk farmaci;

    Abstract : Spray drying is a method with a high potential in the preparation of protein particles suitable for pulmonary delivery. However, surface induced denaturation of bio-molecules during atomization and subsequent drying can be substantial and it is therefore important to develop new formulation concept for concurrent encapsulation and stabilization of proteins during spray drying. READ MORE