Search for dissertations about: "Pharmacoepidemiology"

Showing result 6 - 10 of 24 swedish dissertations containing the word Pharmacoepidemiology.

  1. 6. Adherence to lipid-lowering medications and cardiovascular disease prevention in type 2 diabetes mellitus

    Author : Sofia A. Karlsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medication adherence; refill adherence; medication persistence; pharmacoepidemiology; lipid-lowering medications; type 2 diabetes mellitus; cardiovasular disease; all-cause mortality; cardiovascular mortality; guideline adherence;

    Abstract : Background and aims: Globally, cardiovascular disease (CVD) is the major cause of death among patients with type 2 diabetes mellitus (T2DM). Improved control of LDL cholesterol with lipid-lowering medications and patients’ adherence to such medications have been shown associate with lower risk of CV events and mortality among T2DM patients. READ MORE

  2. 7. Quality of drug treatment in older people from a medical primary care perspective and according to indicators

    Author : Naldy Parodi López; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inappropriate prescribing; older people; pharmacoepidemiology; potentially inappropriate medication; potential prescribing omission; primary health care;

    Abstract : Background: Drug treatment in older people is particularly complex; the burden of disease increases by age, and patients in this age group are more sensitive to drug effects. As a knowledge resource for clinicians as well as for benchmarking and pharmacoepidemiological research, indicators of prescribing quality for older people have been established, including potentially inappropriate medications (PIMs) and potential prescribing omissions (PPOs). READ MORE

  3. 8. Pharmacoepidemiologic studies on cardiovascular drugs - with special reference to the effectiveness and safety of blood pressure lowering drugs

    Author : Juan Merlo; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Farmakologi; toxicology; pharmacy; pharmacognosy; Pharmacological sciences; samhällsmedicin; Socialmedicin; cardiovascular epidemiology; Pharmacoepidemiology; blood pressure; hypertension; cardiovascular drugs; antihypertensive drugs; lipid lowering drugs; nitrates; effectiveness; safety; ecologic studies; Social medicine; cohort studies; farmakognosi; farmaci; toxikologi;

    Abstract : Background: Ischaemic heart disease (IHD) and stroke are the main causes of morbidity and mortality in developed countries and hence constitute a large public health problem. Cardiovascular drugs are used in an effort to prevent (e. g. blood pressure lowering drugs (BPLD) and lipid lowering drugs) and palliate (e. READ MORE

  4. 9. Epidemiological aspects of drug-related vitamin D deficiency and osteoporotic fractures

    Author : Ola Nordqvist; Martin Carlsson; Pär Wanby; Thomas Neumark; Björn Wettermark; Linnéuniversitetet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D; secondary osteoporosis; fractures; drug risk management; medical guideline adherence; electronic health records; real-world data; risk assessment; awareness; attitudes; personalised medicine; cross-sectional study; cohort study; qualitative analysis; thematic analysis; pharmacoepidemiology; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Background: Vitamin D deficiency, secondary osteoporosis and low-energy fractures (LEF) as side effects of specific drugs were first described more than half a century ago. These effects are recognized in guidelines where patients prescribed risk drugs are recommended follow-up with testing and supplementation. READ MORE

  5. 10. Pharmacoepidemiologic Studies of Diabetes Mellitus - with special reference to - Glucose Control and Prognosis of Type 2 Diabetes

    Author : Jonny Olsson; Samhällsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; secreting systems; Endocrinology; cohort study; longitudinal study; cross-sectional study; mortality; diabetes mellitus; Pharmacoepidemiology; prevalence; type 2 diabetes; diabetes costs; short-term sick-leave; premature retirement; production losses; inpatient care; glycaemic control; fasting blood glucose; oral antihyperglycaemic agents; sulphonylurea; metformin; insulin; combination treatment; drug utilization; prescribed daily doses; safety; effectiveness; Endokrinologi; sekretion; diabetologi;

    Abstract : The efficacy and safety of antihyperglycaemic drugs have been evaluated in one American and one British randomized clinical trial, which have given contradictory results. The positive results of the latter may be more convincing as it included a greater number of patients and as its duration was longer. READ MORE