Search for dissertations about: "Pharmacological"

Showing result 11 - 15 of 937 swedish dissertations containing the word Pharmacological.

  2. 11. The premenstrual syndrome : epidemiological, biochemical and pharmacological studies

    Author : Jarmila Hallman; Uppsala universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : .... READ MORE

  4. 12. Cloning, Expression, Pharmacological Characterization and Anatomical Distribution of Melanocortin Receptors in an Evolutionary Perspective

    Author : Aneta I. Ringholm; Helgi B. Schiöth; Dan Larhammar; Björn Olde; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; evolution; melanocortin; MSH; pharmacology; genome duplication; tetraploidization; zebrafish; spiny dogfish; chicken; GPCR; polymorphism; pigmentation; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Abstract : The melanocortin (MC) receptors are G-protein coupled receptors thatparticipate in several important physiological functions such as the regulation of the energy balance. This thesis focuses on the evolutionary aspect of the MC receptors and their pharmacology.One MC4 receptor and two MC5 receptor subtypes were found in a teleost fish, zebrafish. READ MORE

  5. 13. Inhaled pharmacological treatment and critical inhaler technique errors in patients with chronic obstructive pulmonary disease

    Author : Johanna Sulku; Elisabet I. Nielsen; Alf Tunsäter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chronic obstructive pulmonary disease; COPD; critical inhaler technique error; pharmacological treatment; ICS; inhaled corticosteroid; Farmaceutisk vetenskap; Pharmaceutical Science;

    Abstract : Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease characterised by persistent respiratory symptoms and a high risk of exacerbations. Preventive and maintenance pharmacological treatment is primarily administered through handheld inhalers, which are available in several different device-drug combinations. READ MORE

  6. 14. Towards Pharmacological Treatment of Cystic Fibrosis

    Author : Charlotte Andersson; Aleksander Edelman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; cystic fibrosis; airway epithelium; genotype; CFTR; chloride transport; genistein; phenotype; phenylbutyrate; S-nitrosoglutathione; Cellbiologi; Cell biology; Cellbiologi; entomologi; Entomology;

    Abstract : S-nitrosogluthatione is an endogenous substance, present at decreased levels in the lungs of CF patients and was recently found to induce mature CFTR in airway epithelial CF cell lines. We show that S-nitrosoglutathione in physiological concentrations increases the presence of ΔF508 CFTR in the cell membrane and induces cAMP dependent chloride transport in cystic fibrosis airway epithelial cells. READ MORE

  7. 15. Bioactive Compounds in the Chemical Defence of Marine Sponges : Structure-Activity Relationships and Pharmacological Targets

    Author : Erik Hedner; Lars Bohlin; Per R Jonsson; Raffaele Riccio; Uppsala universitet; []
    Keywords : Pharmacognosy; 5-hydroxytryptamine; agelasine; agelasimine; antibacterial; antifouling; barettin; bromobenzisoxazolone barettin; cytotoxic; marine; secondary metabolite; sponge; Farmakognosi; Agelas; Geodia barretti;

    Abstract : Marine invertebrates, in particular sponges, represent a source of a wide range of secondary metabolites, many of which have been attributed various defensive capabilities against environmental stress factors. In this thesis sponge-derived low-molecular peptide-like compounds and associated analogs are investigated for bioactivity and pharmacological targets. READ MORE