Search for dissertations about: "Pharmacological"
Showing result 16 - 20 of 936 swedish dissertations containing the word Pharmacological.
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16. Analytical and pharmacological studies of cyclophosphamide
Abstract : Pharmacokinetic and pharmacodynamic studies are an essential in order to achieve better treatment efficacy and less drug related toxicity. The kinetic studies depend on measuring the drug concentrations in body fluids. READ MORE
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17. Pharmacological therapy of Helicobacter pylori infection
Abstract : The discovery of Helicobacter pylori (H. pylori) opened the doors to new insight and therapy for peptic ulcer disease. Earlier eradication treatment modalities based on bismuth compounds, with or without additional antimicrobials, were not well accepted mainly because of the, at least hypothetical, risks for neurological and/or renal side effects. READ MORE
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18. Novel pharmacological treatment alternatives for schizophrenia
Abstract : Antipsychotic drugs are commonly divided into typical (first generation) and atypical (second generation) antipsychotic drugs. Clinically effective doses of typical antipsychotic drugs generate a striatal dopamine D2 receptor occupancy of about 70 80%, approaching a level that is associated with a high risk of extrapyramidal side effects. READ MORE
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19. A study of potassium channel activation as a pharmacological principle for vasodilation of cerebral blood vessels
Abstract : Increasing [K+]o is intimately coupled to progressive ischemia and reduced CBF. In isolated cerebral and mesenteric arteries, it was found that significant differences in the vascular responses to [K+]o exist. Among the species studied, human cerebral arteries were the most sensitive artery to increasing [K+]o. READ MORE
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20. Mitochondrial permeability transition following calcium overload. - Its role in neuronal cell death and potential as a pharmacological target
Abstract : There is currently no clinically available drug with neuroprotective properties to limit the evolving cell death following e.g. stroke or traumatic brain injury. The mitochondrial permeability transition (mPT) is a potential pathological mechanism causing cell death in the CNS. READ MORE