Search for dissertations about: "Pharmacological"

Showing result 21 - 25 of 937 swedish dissertations containing the word Pharmacological.

  2. 21. Ventricular repolarization in the human heart : effects of pharmacological and non-pharmacological interventions

    Author : Karolina J. Nowinski; Karolinska Institutet; Karolinska Institutet; []
    Keywords : QT interval; QT dispersion; PTCA; ischemia; T vector loop; AV junctional RF ablation; arrhythmia; sex hormones; hormone replacement therapy; cardiac memory ECG; signal-averaged ECG;

    Abstract : Ventricular arrhythmias is the main cause of sudden cardiac death. A prolonged repolarization might cause such arrhythmias, and an increased understanding about mechanisms is therefore important for their primary and secondary prevention. READ MORE

  4. 22. Pharmacological targeting of mutant p53 family members

    Author : Nina Rökaeus; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The tumor suppressor p53 serves as a guardian of the genome and functions mainly as a transcription factor. In response to various stress signals p53 binds to specific DNA sequence motifs and regulates transcription of a large group of target genes involved in cellular processes such as cell cycle arrest, senescence and apoptosis. READ MORE

  5. 23. Severe childhood obesity : behavioural and pharmacological treatment

    Author : Pernilla Danielsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Childhood obesity is a chronic disease associated with increased morbidity, psychosocial problems and reduced life expectancy, all of which is today very common. Despite this, long-term studies of behavioural treatment of childhood obesity are currently lacking. READ MORE

  6. 24. Critical illness myopathy : mechanisms and pharmacological interventions

    Author : Hazem Akkad; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The human body typically contains over 600 skeletal muscles that make up about 40% of total body weight. These muscles work together to perform functions such as locomotion, breathing, mastication, heat regulation and speech. READ MORE

  7. 25. Pharmacological and Developmental Aspects on Neuronal Plasticity

    Author : Lisa Bjartmar; Jan Marcusson; Elias Eriksson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Neuronal plasticity means the ability of the brain, its cells and networks to adapt and adjust to new challenges, a process which is ongoing throughout life. The goal of this thesis was to gain better understanding of the molecular events that follow different types of stimulations of brain structures such as the hippocampus, a key region for cognitive functions with overriding control on the corticosteroid system. READ MORE