Search for dissertations about: "Phosphate homeostasis"

Showing result 1 - 5 of 26 swedish dissertations containing the words Phosphate homeostasis.

  1. 1. The Role of Fibroblast Growth Factor 23 in Phosphate Homeostasis

    Author : Tobias Erik Martin Larsson; Kenneth Jonsson; Östen Ljunggren; Suzanne Jan De Beur; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Fibroblast Growth Factor 23; FGF-23; phosphate homeostasis; vitamin D metabolism; sodium phosphate cotransporters; autosomal dominant hypophosphatemic rickets; ADHR; X-linked hypophosphatemic rickets; XLH; oncogenic osteomalacia; OOM; PHEX; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : The regulation of serum phosphate (Pi) concentrations is a complex process and our current models are far from complete. Due to major advancements in biotechnology and the development of more powerful research tools, recent advances in the field of genetics has led to the identification of several candidates for the long sought-after phosphatonin(s), or Pi regulating hormones. READ MORE

  2. 2. Plastidial phosphate transport in plants

    Author : Patrik Milton Karlsson; Göteborgs universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Arabidopsis; phosphate transport; thylakoid membrane; root plastid; photosynthesis; leaf size; starch metabolism; homology modeling; site-directed mutagenesis;

    Abstract : Phosphorus is an essential element for all living organisms and is central to the genetics and energetics of life. Inorganic phosphate (Pi) is recurrently involved in protein regulation and signal transduction but also in energy transfer as a component of the ATP-molecule. READ MORE

  3. 3. Interorganellar connectivity : From protein to lipid homeostasis

    Author : Carlotta Peselj; Sabrina Büttner; Tim Levine; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Interorganellar connectivity; nucleus; NVJs; chronic lipid bilayer stress; glucose and phosphate exhaustion; nutritional regimes; transmembrane chaperone; IPTP; molekylär biovetenskap; Molecular Bioscience;

    Abstract : Interorganellar connectivity is fundamental for the maintenance of organellar and cellular functionality and viability. This is achieved and maintained by a complex network of signaling cascades, vesicle trafficking between organelles as well as by establishment of direct physical contact at membrane contact sites (MCS). READ MORE

  4. 4. Aspects of Fibroblast Growth Factor 23 in Mild to Moderate Renal Dysfunction

    Author : Per-Anton Westerberg; Torbjörn Linde; Östen Ljunggren; Björn Wikström; Marcus Ketteler; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; FGF23; phosphate; mineral metabolism; elderly; mortality; Medicin; Medicine;

    Abstract : Disturbances in mineral metabolism contribute to vascular calcification and mortality risk in chronic kidney disease (CKD). Serum levels of fibroblast growth factor (FGF)23, a bone derived, phosphaturic peptide, are associated with cardiovascular mortality in CKD. READ MORE

  5. 5. FGF23 - a possible Phosphatonin

    Author : Richard Marsell; Kenneth Jonsson; Caroline Silve; Uppsala universitet; []
    Keywords : Surgery; Fibroblast growth factor 23; FGF23; FGF-23; Phosphate homeostasis; Vitamin D; Klotho; Parathyroid hormone; PTH; Kirurgi;

    Abstract : Human physiology is dependent on an accurate phosphate (Pi) homeostasis. Defective Pi regulation causes hyper- or hypophosphatemia, which are associated with ectopic calcification or impaired bone mineralization, and a shortened life span. Current endocrine models of Pi homeostasis are incomplete. READ MORE