Search for dissertations about: "Physical Chromosome Mapping"

Showing result 1 - 5 of 6 swedish dissertations containing the words Physical Chromosome Mapping.

  1. 1. Genome mapping of the horse

    Author : Gabriella Lindgren; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Horse; microsatellites; linkage analysis; FISH; Type I markers; BAc library; Y chromosome; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Evolutionary Genetics; evolutionär genetik;

    Abstract : Our ability to map and sequence whole genomes is one of the most important developments in biological science. It will provide us with an unprecedented insight into the genetic background of phenotypic traits, such as disease resistance, reproduction and growth and also makes it feasible to study the processes of genome evolution. READ MORE

  2. 2. Genetics of the carbohydrate-deficient glycoprotein syndrome type Ia

    Author : Cecilia Bjursell; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CDG Ia; PMM2; chromosome 16; linkage; linkage disequilibrium; prenatal diagnosis;

    Abstract : In recent years, a revolution in the development of new techniques have made it possible to perform genetic studies of inherited disorders without prior knowledge about the gene product or the function of the gene. The techniques include linkage studies, allelic association studies, physical mapping and the sequencing of candidate genes for finding disease causing mutations. READ MORE

  3. 3. Genetic alterations in Scandinavian neuroblastoma tumors

    Author : Katarina Ejeskär; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuroblastoma; loss of heterozygozity; deletion; 1p; 3p; CDC2L1; TP73; CORT; FHIT;

    Abstract : The results presented here derive from our efforts to find genes and chromosomal regions of interest in the formation and progression of the childhood tumor neuroblastoma.Neuroblastoma is the most common extracranial solid tumor of childhood. READ MORE

  4. 4. Multiple sclerosis : MRI diagnosis, potential treatment and future potential for nanoparticle applications

    Author : Xingchen Wu; Karolinska Institutet; Karolinska Institutet; []

    Abstract : Multiple Sclerosis is an inflammatory demyelinating and neurodegenerative disease of the central nervous system. Magnetic resonance imaging is an important tool for diagnosing of Multiple Sclerosis and for, in vivo, monitoring its evolution of pathology. READ MORE

  5. 5. Alterations of mucin O-glycosylation in response to intestinal infection. Importance of specific glycosyltransferases

    Author : Fredrik J. Olson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Keywords : mucins; altered O-glycosylation; Nippostrongylus brasiliensis infection; blood group A glycosyltransferase; Muc2; MUC1; GalNAc-T4; mass spectrometry;

    Abstract : Mucins are large glycoproteins constituting the major protein component of the mucus layer covering the epithelial surfaces. The mucins are characterised by a dense and heterogeneous O-glycosylation, important for their chemical and physiological properties. READ MORE