Search for dissertations about: "Pia Kotokorpi"

Found 1 swedish dissertation containing the words Pia Kotokorpi.

2. 1. LXR regulation of hepatic gene expression and pituitary dependent hormones

   Author : Pia Kotokorpi; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Liver X receptor; growth hormone; gene regulation; metabolism; hepatocyte; hepatic steatosis; species differences;

   Abstract : The liver X receptors (LXRs) are ligand activated transcription factors involved in the regulation of metabolic genes. LXRs are considered potential drug targets to treat metabolic disorders, however, unwanted side effects, as revealed from rodent studies, include increased lipogenesis in the liver and increased plasma triglyceride levels. READ MORE