Search for dissertations about: "Pim1"

Found 2 swedish dissertations containing the word Pim1.

  2. 1. Early oncogenic events and defective apoptosis in prostate cancer

    Author : Xiaolei Fang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Prostate cancer; HGPIN; ezrin; pim-1; XAF1; apoptosis; DNA methylation; immunohistochemistry; FISH;

    Abstract : Prostate cancer is one of the most common malignancies in males in the Western world. Although the mechanisms are unclear, it is generally believed that the accumulation of genetic alterations leads to the tumor formation. READ MORE

  4. 2. Examining the role of metabolism in Myc-driven tumorigenesis

    Author : Tacha Zi Plym Forshell; Jonas Nilsson; Mattias Belting; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; cancer; Myc; metabolism; polyamines; spermidine synthase; glycolysis; lactate dehydrogenase; serine metabolism; Phgdh; folate metabolism; Shmt; Pim kinase; Pim-3 Kinase; Molecular biology; Molekylärbiologi;

    Abstract : Myc transcriptionally regulates genes involved in processes such as cell proliferation, metabolism, differentiation, and angiogenesis.  MYC expression is deregulated in many types of human cancer; therefore discovering the mechanisms behind MYCs role in tumorigenesis is essential. READ MORE