Search for dissertations about: "Piotr Wardęga"

Found 1 swedish dissertation containing the words Piotr Wardęga.

2. 1. Regulation of PDGFRβ signaling 

   Author : Piotr Wardęga; Johan Lennartsson; Edvard Smith; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; PDGF; HD-PTP; Alix; Cbl; Ub; Fer; Y857; Y771; downregulation; degradation; ubiquitination; activation loop; Cell and molecular biology; Cell- och molekylärbiologi; Medical Cell Biology; Medicinsk cellbiologi;

   Abstract : Platelet-derived growth factor (PDGF) isoforms, which bind to closely related a- and b-tyrosine kinase receptors, induce migration, proliferation, survival and differentiation of mesenchymal cells. They signal by the active receptor attracting Src homology 2 (SH2) domain containing proteins, which subsequently initiate a set of signaling pathways. READ MORE