Search for dissertations about: "Piperaquine"
Showing result 1 - 5 of 11 swedish dissertations containing the word Piperaquine.
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1. Piperaquine - Bioanalys, drug metabolism and pharmacokinetics
Abstract : Malaria is one of the most abundant parasitic diseases in the world affecting many of the poorest economies. The estimated prevalence is 300 to 700 million clinical episodes each year with up to 3 million deaths. READ MORE
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2. Piperaquine and Metabolites - Bioanalysis and Pharmacokinetics
Abstract : Antimalarial piperaquine (PQ) is currently used as a partner drug with dihydroartemisinin (DHA), exhibiting high cure rates (>95%) for P. falciparum. Despite its raising usage worldwide with DHA, PQ is synthetically developed outside of big pharma pipelines. READ MORE
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3. Drug Analysis : Bioanalytical Method Development and Validation
Abstract : This thesis describes bioanalytical methods for drug determination in biological matrixes, with drugs in focus used against diseases largely affecting low-income countries. Solid-phase extraction is used for sample cleanup, and processed samples are analyzed by liquid chromatography. READ MORE
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4. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids
Abstract : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. READ MORE
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5. Development of field-adapted analytical methods for the determination of new antimalarial drugs in biological fluids
Abstract : .... READ MORE