Search for dissertations about: "Pityrosporum"

Found 4 swedish dissertations containing the word Pityrosporum.

  1. 1. Immunological mechanisms in atopic dermatitis : clinical and experimental studies

    Author : Maria Tengvall Linder; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; atopic dermatitis; Cyclosporin A; cytokines; eosinophils; lgE; lgE receptors; Pityrosporum orbiculare; patch test; skin biopsy specimens; T cells;

    Abstract : The aim of the study was to investigate immunological mechanisms in atopic dermatitis. Serum IgE levels are elevated in 80% of atopic dermatitis patients and CD4+ T cells and environmental allergens are known to be of importance in the pathogenesis of the disease. READ MORE

  2. 2. The role of Malassezia in the pathogenesis of atopic eczema/dermatitis syndrome

    Author : Catharina Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Atopic dermatitis; atopic eczema dermatitis syndrome; Malassezia; Pityrosporum; T-cells; PBMC proliferation; cytokines; ELISPOT; TCRVB; IgE; skin prick test; atopy patch test;

    Abstract : Atopic eczema/dermatitis syndrome (AEDS) is a chronically relapsing skin disease, which is often associated with elevated levels of serum lgE. The immunopathology of AEDS is at present unclear, but it is known that lymphocytes infiltrating the AEDS lesions are predominantly of the CD4+ T helper phenotype. READ MORE

  3. 3. Identification and characterization of allergen components of the opportunistic yeast Malassezia furfur

    Author : Arezou Zargari; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; allergen; atopic dermatitis; baculovirus; Candida albicans; CAP RAST; cDNA; confocal laser scanning microscopy; Escherichia coli; IgE; Malassezia furfur; monoclonal antibody; Pityrosporum orbiculare; recombinant allergen; yeast.;

    Abstract : The yeast Malassezia furfur (Pityrosporum orbiculare) is a member of the human norrnal skin microflora. It has been suggested that this yeast plays an important role in the pathogenesis of atopic dermatitis (AD). In 40-65% of patients with AD anti-M. furfur activity has been shown with skin tests and/or specific IgE serology. READ MORE

  4. 4. Analysis of human epidermal Langerhans' cells and allergens with confocal laser scanning microscopy

    Author : Axel Emilson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; 3-D analysis; allergen; allergic contact dermatitis; basal cellcarcinoma; Bet v I; birch; confocal laser scanning microscopy; epidermis; HLA-DR; image analysis; invariant chain; irritant contact dermatitis; Langerhans cell; occlusion; P. orbiculare;

    Abstract : Analysis of human epidermal Langerhans' cells and allergenswith confocal laser scanning microscopy By Axel Emilson From the Department of Laboratory Medicine, Division of ClinicalImmunology, Karolinska Institute and Hospital, and the Department of Medical Biophysics,MBB, Karolinska Institute, Stockholm, Sweden The aim of the thesis was to explore confocal laser scanning microscopy (CLSM)as a tool for 1) quantitative and 3-dimensional (3-D) analysis of the human antigen-presentingLangerhans' cell (LC) in epidermis and 2) for localization of allergens in yeastcells and in birch pollen. Epidermal LCs were investigated after occlusion with patchtests and in basal cell carcinoma (BCC) skin. READ MORE