Search for dissertations about: "Placenta metabolism"

Showing result 1 - 5 of 21 swedish dissertations containing the words Placenta metabolism.

  1. 1. The Role of Mammalian Target of Rapamycin in the Regulation of Amino Acid Transporters in the Human Placenta

    Author : Sara Roos; Göteborgs universitet; []
    Keywords : amino acids; fetal growth restriction; human; mammalian target of rapamycin; membrane transporters; metabolism; placenta; pregnancy; system A; system L; taurine transporter;

    Abstract : Abnormal fetal growth, which is associated with both perinatal morbidity as well as metabolic diseases in adulthood, is an important clinical problem affecting as many as 15% of all pregnancies. However, to this date, there is no specific treatment of this condition. READ MORE

  2. 2. Placental LPL and glucose metabolism in complicated pregnancies

    Author : AnneLiese Magnusson-Olsson; Göteborgs universitet; []
    Keywords : placenta; intrauterine growth restriction; insulin dependent diabetes mellitus; lipoprotein lipase; fatty acids; fatty acid binding proteins; cytotrophoblasts;

    Abstract : BACKGROUND: Pregnancies complicated by intrauterine growth restriction (IUGR) or diabetes are associated with alterations in both lipid and glucose metabolism, which may lead to long lasting metabolic disturbances in the fetus and susceptibility for developing metabolic syndrome in postnatal life. Glucose is the major energy source for both the fetus and placenta. READ MORE

  3. 3. Localization of lipoprotein lipase in mouse pancreas, kidney and placenta : impact of metabolic disturbances on cellular distribution and activity regulation

    Author : Rakel Nyrén; Gunilla Olivecrona; Paolo Parini; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lipoprotein lipase; pancreas; kidney; placenta; angiopoietin-like protein 4; high-fat diet; obesity; mice; PET CT; nutritional status; triglyceride; GPIHBP1; medicinsk och fysiologisk kemi; Medical and Physiological Chemistry;

    Abstract : Lipoprotein lipase (LPL) is the key enzyme for metabolism of triglycerides in plasma lipoproteins. In recent years many new facts about the enzyme and its regulation have been uncovered. The endothelial membrane protein GPIHBP1 translocates LPL through endothelial cells and holds the enzyme in place at the luminal side of the capillary endothelium. READ MORE

  4. 4. Placental Function : An Epidemiological and Magnetic Resonance Study

    Author : Sara Sohlberg; Anna-Karin Wikstrom; Matts Olovsson; Ajlana Mulic-Lutvica; Johan Wikström; Karel Marsal; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; body height; body mass index; early preeclampsia; late preeclampsia; magnetic resonance imaging; placenta; perfusion; IVIM; risk factors; energy metabolism; magnetic resonance spectroscopy; 31P-MRS; Obstetrik och gynekologi; Obstetrics and Gynaecology;

    Abstract : Placental function is central for normal pregnancy and in many of the major pregnancy disorders. We used magnetic resonance imaging techniques to investigate placental function in normal pregnancy, in early and late preeclampsia and in intrauterine growth restriction. READ MORE

  5. 5. Investigating the source of free fetal hemoglobin in preeclampsia. The role of the placenta and the fetus

    Author : Zahra Masoumi; Lund Obstetrik och gynekologi; []
    Keywords : Preeclampsia pregnancy; Placenta; Umbilical cord blood; Fetal erythropoiesis; Non-erythroid globin;

    Abstract : Preeclampsia (PE) is an important pregnancy complication that affects 3-8% of women worldwide and is a leading cause of maternal and fetal morbidity and mortality. It is known that PE is associated with placental dysfunction, resulting in hypoxia, oxidative stress, altered metabolism and production of inflammatory cytokines. READ MORE