Search for dissertations about: "Plasma cytology"

Showing result 1 - 5 of 13 swedish dissertations containing the words Plasma cytology.

2. 1. Pathophysiology of 5-fluorouracil induced cardiotoxicity : a clinical and experimental study

   Author : Magdalena Cwikiel; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; cell culture.; scanning and transmission electron microscopy; endothelium; lipid peroxidation; free radical; fibrinogen; 5-fluorouracil; blood and plasma viscosity; cardiotoxicity; cancerology; Cytologi; onkologi; cancer; Pharmacological sciences; pharmacognosy; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

   Abstract : This thesis concerns the pathophysiology of 5-fluorouracil (5-FU) induced cardiotoxicity. The aim of the clinical studies was to determine whether hemorheological factors might explain 5-FU cardiotoxicity (I) and if the syndrome was associated with free radical (FR) generation and lipid peroxidation (II). READ MORE

4. 2. Membrane protein proteomics - Novel method for membrane protein identification and quantification

   Author : Maria Bentz; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biokemisk teknik; mebran; steroider; Lipider; membranes; steroids; Lipids; enzymologi; Proteiner; Membrane proteins; Proteomics; Proteinase K; N-terminal labelling; Relative Quantitation; Database search; Cancer; Cytology; oncology; cancerology; Cytologi; onkologi; cancer; enzymology; Proteins; Biochemical technology;

   Abstract : Membrane proteins are fairly refractory to digestion especially by trypsin. Less specific proteases like elastase and pepsin are much more effective. However database searching using non-tryptic peptides is much less effective due to the lack of charge localisation at the N- and C-termini and the absence of sequence specificity. READ MORE

5. 3. REGULATED UPTAKE OF BIOPOLYMERS Role of cell surface proteoglycans Implications for drug and gene delivery

   Author : Staffan Sandgren; Bröstcancer-genetik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Cytology; oncology; proliferation; differentiation; Medicine human and vertebrates ; growth factor; cancer; drug delivery; gene therapy; LL-37; HIV-Tat; cell penetrating peptides; polyamines; heparan sulfate; onkologi; Cytologi; cancerology; internalization; proteoglycans;

   Abstract : Cells continuously export, import, and recycle molecules over the plasma membrane. Internalization, i.e. cellular import of extracellular material, is a fundamental process, which provides cells with nutrients and enables the immune cells of higher organisms to remove debris, sample their surroundings for antigens and to fight microbes. READ MORE

6. 4. Alpha 1-antitrypsin: A Role in Cancer Progression

   Author : Inga Zelvyté; Malmö Institutionen för kliniska vetenskaper; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cancer; onkologi; Cytologi; cancerology; oncology; Cytology; invasion; neutrophils; cancer cell; Alpha1- antitrypsin; proteinase inhibitors;

   Abstract : Alpha1-antitrypsin (AAT), a circulating single-chain glycoprotein is the most abundant serine proteinase inhibitor in human plasma. AAT is an acute phase protein, its levels increase rapidly to concentrations exceeding 50mM in response to inflammation, infection and malignant diseases. READ MORE

7. 5. Genomic and Molecular Aspects of Mature Human B Cells

   Author : Carl-Magnus Högerkorp; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; transplantation; Human; B-cell; Germinal center; Centroblast; serology; Immunology; onkologi; cancer; Cytologi; cancerology; oncology; Microarray; Cytology; Mantel cell lymphoma; Immunologi; serologi; Centrocyte;

   Abstract : This thesis covers aspects of the mature human B cell and its different guises on its way to become a fully differentiated antibody forming plasma cell (AFC), the key player in the humoral immune system. The understanding of the complex molecular mechanisms taking place in the B cell, as it first encounters antigen, enters the germinal center (GC) reaction, giving rise to memory cells and plasma cells, is not only of importance for the curious scientist, but will also benefit the understanding of B cells in disease. READ MORE