Search for dissertations about: "Plasmodium falciparum"

Showing result 16 - 20 of 133 swedish dissertations containing the words Plasmodium falciparum.

  2. 16. Host cell adhesion of Plasmodium falciparum-infected erythrocytes

    Author : Carl Johan Treutiger; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Plasmodium falciparum; erythrocyte rosetting; cytoadherence; cerebral malaria; PfEMPI; serum proteins; PECAM-I CD31;

    Abstract : Excessive binding of Plasmodium falciparum-infected erythrocytes to the microvascular endothelium (cytoadherence) and to uninfected eryrthrocytes (rosetting) are regarded as key-events in the development of a severe malaria infection. P. falciparum rosetting was confirmed to be associated with the development of cerebral malaria in The Gambia. READ MORE

  4. 17. New strategies and tools for Plasmodium falciparum case management and surveillance in the era of imminent resistance to artemisinin-based combination therapy in Tanzania

    Author : Lwidiko E Mhamilawa; Andreas Mårtensson; Billy Ngasala; Ulrika Morris; Ib Christian Bygbjerg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malaria; Plasmodium falciparum; artemether-lumefantrine; drug resistance; Tanzania; Medicinsk vetenskap; Medical Science;

    Abstract : Artemether-lumefantrine has been an efficacious first line treatment for uncomplicated Plasmodium falciparum malaria in Tanzania since its introduction in 2006. Interest has developed in understanding the observation of high residual PCR determined positivity rates on day 3 after supervised artemether-lumefantrine treatment in the magnitude of almost 30% in previous assessments from 2015 in Bagamoyo district, Tanzania. READ MORE

  5. 18. Antibody responses in Plasmodium falciparum malaria and their relation to protection against the disease

    Author : Ahmed Kamal Bolad; Klavs Berzins; Lars Hviid; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunity; parasital immunology; Plasmodium falciparum malaria; antibody mediated invasion growth inhibition; Immunology; Immunologi;

    Abstract : Protective immunity against Plasmodium falciparum may be obtained after repeated exposure to infection. Several studies indicate that immunity against the blood stages of the P. Falciparum infection is mainly antibody mediated. READ MORE

  6. 19. Heparan sulfate dependent sequestration during Plasmodium falciparum malaria

    Author : Anna Vogt; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Severe malaria; Plasmodium falciparum; sequestration; endothelial adhesion; erythrocyte rosetting; PfEMP1; DBL1alpha; heparan sulfate; heparin; animal model.;

    Abstract : Plasmodium falciparum infected erythrocytes are able to bind to the microvascular endothelium (cytoadherence), and to uninfected erythrocytes (rosetting) that lead to excessive sequestration of the parasites. This causes obstruction of the deep microvasculature by P. READ MORE

  7. 20. Exploring B cell responses in Plasmodium falciparum malaria

    Author : Caroline Rönnberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Plasmodium falciparum malaria remains one of the most devastating infectious diseases today. Small children in sub-Saharan Africa carry the heaviest burden of morbidity and mortality. Immunity to malaria is not well understood, although humoral immunity has proven an integral part of protection from disease. READ MORE