Search for dissertations about: "Platelet"
Showing result 21 - 25 of 483 swedish dissertations containing the word Platelet.
-
21. Platelet activation and cytokine release during experimental extracorporeal circulation
Abstract : .... READ MORE
-
22. Platelet transfusions in hematological disorders
Abstract : Platelets are important for clot formation and vascular integrity. Thrombocytopenic patients with hematological disorders are at risk of bleeding and platelet transfusions are important in supportive care and treatment of lite-threatening bleedings. READ MORE
-
23. Platelets – Multifaceted players in tumor progression and vascular function
Abstract : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. READ MORE
-
24. Genetic studies on cardiovascular disease - identification of novel drug targets
Abstract : The aim of this thesis was to identify novel potential drug targets of cardiovascular disease with a focus on G-protein coupled receptors. We identified a common genetic variant of the ATP receptor P2Y11, where an alanine is substituted with a threonine at position 87 of the P2Y11 receptor that increases the risk of developing acute myocardial infarction. READ MORE
-
25. Streptococcus pyogenes and its interactions with the human host
Abstract : We have found that a set of group A streptococcal strains, primarily associated with skin infections, express surface-associated M proteins that bind plasminogen and plasmin with high affinity. The binding is mediated by a common 13 amino acid internal repeated sequence located in the NH2-terminal surface-exposed portion of these M proteins. READ MORE