Search for dissertations about: "Poly-Glutamine"

Found 1 swedish dissertation containing the word Poly-Glutamine.

2. 1. Alterations in activity and specificity of intracellular proteolysis in disease pathogenesis

   Author : Lei Lu; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Proteasome; Ubiquitin; Cancer; Neuro-degeneration; Poly-Glutamine; Apoptosis; Tripeptidyl-Peptidase II; Stress; IAP;

   Abstract : The ubiquitin-proteasome pathway (UPP) plays a fundamental role in many basic cellular processes. Virtually all events in cellular physiology include control by the ubiquitin-proteasome pathway. Ubiquitinated substrates are degraded by the 26S proteasome, a large multicatalytic protease complex. READ MORE