Search for dissertations about: "Polymerase chain reaction"

Showing result 1 - 5 of 213 swedish dissertations containing the words Polymerase chain reaction.

  2. 1. Statistical modelling in chemistry - applications to nuclear magnetic resonance and polymerase chain reaction

    Author : Halfdan Grage; Teknisk mikrobiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Statistik; operationsanalys; programmering; aktuariematematik; programming; actuarial mathematics; Statistics; operations research; experimental design.; logistic regression; detection probability; region of operability; sampling. Diagnostic PCR; Cramér-Rao bounds; maximum likelihood estimation; NMR spectroscopy; Gaussian noise;

    Abstract : This thesis consists of two parts with the common theme of statistical modelling in chemistry. The first part is concerned with applications in nuclear magnetic resonance (NMR) spectroscopy, while the second part deals with applications in polymerase chain reaction (PCR). READ MORE

  4. 2. On the Versatility of Microwave-Assisted Chemistry : Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry

    Author : Kristina M. Orrling; Mats Larhed; Fredrik Almqvist; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microwave-assisted chemistry; malaria; aspartic protease; plasmepsin; PfPM4; PmPM4; PoPM4; PvPM4; inhibitor; unsaturated lactone; unsaturated lactam; unsaturated amide; lactam; Bestmann s ylide; ionic liquid; polymerase chain reaction; thermophilic enzyme; Pharmaceutical chemistry; Läkemedelskemi; Organic synthesis; Organisk syntes; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE

  5. 3. On community acquired infections requiring intensive care

    Author : Magnus Brink; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intensive care; infection; acute bacterial meningitis; beta-lactam antibiotics; cerebrospinal fluid; polymerase chain reaction; immunochromatographic test; influenza A H1N1; pandemic; non-invasive ventilation; necrotizing soft-tissue infection; inter-hospital transfer;

    Abstract : Acute bacterial meningitis (ABM), influenza, and necrotizing soft-tissue infections (NSTIs) are diseases that in a short period of time can progress to become life threatening. Individuals with severe forms of these infections must be treated in an intensive care unit were monitoring and support of failing organs improve the chances of survival. READ MORE

  6. 4. Chlamydia pneumoniae in Children - Epidemiology and Clinical Implications

    Author : Erik Normann; Björn Wettergren; Håkan Gnarpe; Claes Sundelin; Birger Trollfors; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pediatrics; allergy; asthma; children; Chlamydia pneumoniae; immunohistochemistry; microimmunofluorescence; polymerase chain reaction; respiratory tract infection; Pediatrik; Paediatric medicine; Pediatrisk medicin;

    Abstract : Chlamydia pneumoniae is a human respiratory tract pathogen. Seroepidemiological studies indicate that C. pneumoniae infection is most common in school-aged children and infrequently detected in younger children.The aims of this study were to further elucidate the prevalence of C. READ MORE

  7. 5. Detection and Characterisation of Salmonella in Animal Feed Samples by PCR-Based Methods

    Author : Charlotta Löfström; Teknisk mikrobiologi; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; Livsmedelsteknik; Biotechnology; Bioteknik; Biokemisk teknik; Biochemical technology; Analytisk kemi; Analytical chemistry; mykologi; virologi; bakteriologi; Mikrobiologi; validation; Microbiology; bacteriology; virology; mycology; Salmonella; ribotyping; detection; animal feed; randomly amplified polymorphic DNA; pulsed-field gel electrophorsis; pre-PCR processing; PCR; polymerase chain reaction; genotyping;

    Abstract : Animal feed is a recognised source of Salmonella enterica for farm livestock and may also indirectly cause infection in people consuming foods of animal origin. It is therefore important to have rapid, reproducible and specific methods for the detection of Salmonella in feed, and for the characterisation of strains for further epidemiological investigations or to trace the source of contamination in a production facility. READ MORE