Search for dissertations about: "Polymerase gamma"
Showing result 1 - 5 of 21 swedish dissertations containing the words Polymerase gamma.
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1. Crisis in Energy Metabolism - Mitochondrial Defects and a New Disease Entity
Abstract : Impairment of energy metabolism may be associated with severe implications for affected individuals since all fundamental cell functions are energy-dependent. Disorders of energy metabolism are often genetic and associated with defects in the oxidative phosphorylation in mitochondria. READ MORE
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2. The consequences of DNA lesions for mitochondrial DNA maintenance
Abstract : Eukaryotic cells have their own energy-producing organelles called mitochondria. The energy is stored in the adenosine triphosphate (ATP) molecule and is produced via the oxidative phosphorylation process inside the mitochondria. Thirteen of the essential proteins required for this process are encoded on the mitochondrial DNA (mtDNA). READ MORE
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3. Molecular mechanisms of mammalian mitochondrial DNA replication and transcription
Abstract : Mitochondria are cytoplasmic organelles in eukaryotic cells, mainly devoted to the synthesis of ATP, through the Oxydative Phospshorylation System (OXPHOS). The organelle has its own genome, the mitochondrial DNA (mtDNA) that encodes for all the RNA components of the mitochondrial translation apparatus (two rRNAs and 22 tRNAs) and for 13 subunits of the OXPHOS complexes. READ MORE
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4. Immunological studies in the brain and signaling pathways in experimental African trypanosomiasis
Abstract : African Trypanosomiasis is a disease prevalent among humans and animals in tropical Africa which is caused by the extracellular hemoflagellate Trypanosoma brucei (T. b.). READ MORE
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5. Studies on uptake and effect of triclosan on production of inflammatory mediators in human gingival fibroblasts
Abstract : Triclosan (2,4,4'-trichloro-2'-hydroxy-diphenyl ether) is a lipid soluble anti-bacterial agent widely used in dentifrices, mouthrinses, soap and cosmetics. Although reports on the efficacy of triclosan on periodontal diseases are conflicting, it is documented in clinical studies that dentifrices containing triclosan reduce plaque accumulation and improve gingival health. READ MORE