Search for dissertations about: "Polysaccharide vaccine"

Showing result 1 - 5 of 28 swedish dissertations containing the words Polysaccharide vaccine.

  2. 1. Infectious and bleeding complications in patients with hematological malignancies : Studies on diagnosis and prevention

    Author : Tobias Svensson; Honar Cherif; Martin Höglund; Jan Sjölin; Christine Wennerås; Uppsala universitet; []
    Keywords : Chronic lymphocytic leukemia; Immunodeficiency; Hypogammaglobulinemia; IgG subclass; Pneumococci; Pneumococcal vaccine; Polysaccharide vaccine; Protein-conjugate vaccine; Aspergillosis; Bronchoalveolar lavage; Invasive fungal disease; Pneumocystis jirovecii pneumonia; Myelodysplastic syndrome; Azacitidine; Eltrombopag; Thrombocytopenia; Thrombopoietin receptor; Oncology; Onkologi;

    Abstract : The overall aim of this thesis is to improve knowledge about the prevention of infectious and bleeding complications in patients with hematological malignancies, primarily in those with chronic lymphocytic leukemia (CLL) and myelodysplatic syndrome (MDS).Hypogammaglobulinemia, impaired production of immunoglobulins (Ig), is an established risk factor for infection, but the impact of IgG pure subclass deficiency (IgG subclass deficiency with adequate production of IgG, IgA, and IgM) has been debated. READ MORE

  4. 2. Impact of the inflammatory response on specific immunity in neurosurgical patients

    Author : Anna Ljunghill Hedberg; Jan Sjölin; Karlis Pauksen; Lars Hagberg; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; T-cell-dependent vaccine; T-cell-independent vaccine; CNS injury-induced immune deficiency syndrome; pneumococcal conjugate vaccine; pneumococcal polysaccharide vaccine; posttraumatic meningitis.; Medicinsk vetenskap; Medical Science; Infektionssjukdomar; Infectious Diseases;

    Abstract : Vaccination with a T-cell-dependent pneumococcal conjugate vaccine (PCV) followed by a T-cell-independent pneumococcal polysaccharide vaccine (PPSV) is recommended after basilar skull fracture to reduce the risk of meningitis. The optimal time frame for vaccination has not yet been established and varies widely in practice. READ MORE

  5. 3. Broadly protective nanoparticle-based mucosal vaccine against influenza virus infection

    Author : Valentina Bernasconi; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucosal vaccination; Influenza A virus; CTA1-DD; Nanoparticle; Targeted adjuvant; Nasal immunization; Oral immunization; Neonatal vaccine; Universal vaccine;

    Abstract : Influenza is one of the major viral diseases affecting humans and it is responsible for three to five million cases of severe illness and about 250.000 to 500.000 deaths each year worldwide. READ MORE

  6. 4. Immunogenicity and protective potential of Protein D of Haemophilus influenzae against H. influenzae infection

    Author : Mustafa Akkoyunlu; Malmö Klinisk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bactericidal assay; mucosal immunity; otitis media; vaccine; H. influenzae; protein D; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : Both Haemophilus influenzae type b (Hib) and nontypeable H. influenzae (NTHi) are important human pathogens causing invasive and mucosal infections. Currently there are number of vaccines available against Hib infections. READ MORE

  7. 5. Molecular studies on streptococcal surface proteins

    Author : Johan Waldemarsson; Avdelningen för medicinsk mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nonimmunodominance; vaccine; camouflaging; Streptococcus agalactiae; leucine-rich repeat; Streptococcus pyogenes; alpha; fibrinogen; M protein; surface proteins; Rib;

    Abstract : Streptococcus agalactiae and Streptococcus pyogenes are two related human pathogens causing different diseases. This thesis focuses on a number of surface proteins expressed by S. agalactiae and S. pyogenes and, more specifically, the molecular and biological characterization of these proteins. READ MORE