Search for dissertations about: "Poonam Ahuja Jensen"

Found 1 swedish dissertation containing the words Poonam Ahuja Jensen.

2. 1. rd1 Photoreceptor Degeneration: Photoreceptor Rescue and Role of Metalloproteases in Retinal Degeneration

   Author : Poonam Ahuja Jensen; Allmänmedicin och samhällsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oftalmologi; Ophtalmology; retinal degeneration; Survival factors; metalloproteases;

   Abstract : The thesis is focused on an attempt to delay photoreceptor cell death in the rd1 mouse using Lens Epithelium Derived Growth Factor (LEDGF), Glutathione S-Transferase mu (GST-?? and Glutathione S-Transferase alpha (GST-?? in an organ culture paradigm as well as the role of metalloproteases (MMPs) and their tissue inhibitors in photoreceptor degeneration (TIMPs). The rd1 mouse model displays a retina degeneration which starts around day 10 with rod photoreceptor cell death. READ MORE