Search for dissertations about: "Prostate antigens"

Showing result 1 - 5 of 13 swedish dissertations containing the words Prostate antigens.

2. 1. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

   Author : Björn Carlsson; Magnus Essand; Thomas Tötterman; Malcolm Brenner; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; Immunology; Immunologi;

   Abstract : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. READ MORE

4. 2. Regulatory Proteins in Progenitors and Differentiated Cells of the Human Prostate

   Author : Jens Ceder; Malmö (Abrahamsson) Urologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; somatostatin; transit amplifying cells; cell differentiation; adult stem cells; Prostate gland; prostatic benign hyperplasia; neuroendocrine cells; prostate cancer;

   Abstract : Prostate cancer (PC) develops from an androgen-dependent tissue that contains androgen receptors in both the stromal and glandular compartments. Surgical removal of the prostate may cure the patient, but if metastatic spread has occurred, androgen suppression therapy is the standard treatment. READ MORE

5. 3. Generation of Therapeutic T Cells for Prostate Cancer

   Author : Ole Forsberg; Magnus Essand; Thomas Tötterman; Gustav Gaudernack; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; T cells; dendritic cells; peptides; cytomegalovirus; adenovirus; immunotherapy; Clinical immunology; Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

   Abstract : The work presented herein focuses on the activation of the adaptive immune system in order to develop T cell-based immunotherapy for viral infections and cancer. The main goal was to identify and activate viral or tumoral antigen-specific T cells by using different identification, isolation and stimulation techniques. READ MORE

6. 4. Preclinical imaging of prostate cancer using radiolabeled antibodies

   Author : Susan Evans Axelsson; Malmö Urologisk cancerforskning; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : Target-specific molecular imaging with radiolabeled antibodies has experienced a rapid growth over the past 20 years, and is now an essential tool to provide information on disease presence and extent. Despite all efforts to detect and control prostate cancer at an early stage, a number of men are still progressing to develop incurable metastatic disease. READ MORE

7. 5. Functionally-associated target antigens in cancer. Defined by human antibodies and small interfering RNAs

   Author : Johan Fransson; Institutionen för immunteknologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phage display; Antibody; cancer; transplantation; Immunologi; serologi; serology; Immunology; onkologi; Cytologi; cancerology; oncology; Biochemistry; Metabolism; Biokemi; metabolism; Biotechnology; Bioteknik; Cytology;

   Abstract : Cancer is the collective name for diseases that have one thing in common ? uncontrolled cell growth. The increase in cancer cell proliferation eventually results in tumor formation and, in the worst case, metastatic spread to other organs. Common treatment modalities of cancer include chemotherapy and radiation therapy. READ MORE