Search for dissertations about: "Prostate-specific antigen"

Showing result 1 - 5 of 85 swedish dissertations containing the words Prostate-specific antigen.

  1. 1. Metabolism of free and complexed prostate - specific antigen and their utility for diagnosis and prognosis of prostate cancer

    Author : Thomas Björk; Malmö Urologisk cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; benign prostatic hyperplasia; alpha-1-antichymotrypsin; PSA; prostate cancer; prostate-specific antigen; Urology; nephrology; Urologi; nefrologi;

    Abstract : Prostate-specific antigen (PSA) is a glycoprotein produced by the prostate gland. It occurs in several molecular forms in the blood and assays have been developed to measure free PSA and PSA in complex with alpha-1-antichymotrypsin (PSA-ACT). READ MORE

  2. 2. Impact of renal dysfunction on serum Prostate-Specific Antigen

    Author : Laila Bruun; Internmedicin - epidemiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Urologi; hK2; Urology; intra-individual variation; elimination; peritoneal dialysis; renal dysfunction; kidney transplantation; hemodialysis; nefrologi; nephrology; PSA;

    Abstract : Measurement of prostate-specific antigen (PSA) in blood is an important tool in detection for prostate cancer. PSA occurs in several molecular forms in blood: mainly as a free form with a molecular mass of 28 kDa; and as PSA complexed to alpha-1-antichymotrypsin, complexed PSA, with a molecular mass of 90 kDa. READ MORE

  3. 3. Structure, evolution and expression of glandular kallikrein genes

    Author : Yvonne Ceder; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ileum.; Clinical chemistry; Klinisk kemi; Tissue distribution; Androgen responsive element; Ortholog; Evolution; Prostate cancer; Glandular kallikreins; Prostate-specific antigen;

    Abstract : Prostate-specific antigen (PSA) is a worldwide used tool for the diagnosis and monitoring of prostate cancer. It is a serine protease and belongs to the family of glandular kallikreins. Humans have three classical glandular kallikreins, but it has been reported that rodents have many more. READ MORE

  4. 4. Biochemical Studies of Semenogelins with Emphasis on Zinc-Binding Properties

    Author : Magnus Jonsson; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sexualitet; sexuality; Obstetrik; gynekologi; andrologi; reproduction; andrology; gynaecology; Obstetrics; Klinisk kemi; Clinical chemistry; gel-forming proteins; surface plasmon resonance; prostate-specific antigen; protein C inhibitor; seminal plasma; zinc; semen; semenogelin; reproduktion;

    Abstract : Semenogelins I and II (SgI and SgII) are homologous and rapidly evolving proteins that have a repetitive primary structure and are synthesized mainly in the seminal vesicles. Upon ejaculation, a gelatinous coagulum is formed when the semenogelin-rich secretion from the seminal vesicles is mixed with the prostate secretion, which contains high concentrations of zinc(II) and proteases. READ MORE

  5. 5. Magnetic Resonance Imaging as a Screening Tool for Prostate Cancer

    Author : Kimia Kohestani; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; prostate cancer; prostate-specific antigen; magnetic resonance imaging; screening; early detection;

    Abstract : The overall aim of this thesis was to explore the role of Magnetic resonance imaging (MRI) of the prostate as an adjunct to the prostate-specific antigen (PSA)-test in screening for prostate cancer (PCa), focusing on the performance of MRI in detecting clinically significant PCa within the randomised controlled GÖTEBORG Prostate Cancer Screening 2 Trial. By inviting men 50–60 years of age to different screening strategies—PSA cut-off for biopsy 3. READ MORE