Search for dissertations about: "Protein Model Quality Assessment"

Showing result 11 - 15 of 15 swedish dissertations containing the words Protein Model Quality Assessment.

  2. 11. Aggressive lymphoma

    Author : Mats Jerkeman; Bröstcancer-genetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; BCL6 rearr; 1q21-23; cytogenetics; histopathology; P-glycoprotein; p53; BCL2; Ki-67; immunohistochemistry; proliferation; dose intensity; health-related quality of life; International Prognostic Index; prognostic factors; aggressive lymphoma; chemotherapy; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; cancer; onkologi; Cytologi; cancerology; oncology;

    Abstract : Aggressive lymphoma is a rapidly growing tumour of lymphocyte origin, potentially curable with chemotherapy. In a trial by the Nordic Lymphoma Group, 405 patients with aggressive lymphoma were included, and randomised to receive either the standard chemotherapy regimen, CHOP, or a weekly multidrug regimen, MACOP-B. READ MORE

  4. 12. Algorithms for building and evaluating multiple sequence alignments

    Author : Timo Lassmann; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Bioinformatics; sequence analysis; sequence alignment; multiple sequence alignment;

    Abstract : The alignment of biological sequences is crucial for the transfer of annotation from model organisms to humans. Pairwise alignment of sequences can reveal homology while multiple alignments are used to characterize protein families and elucidate their evolutionary history. READ MORE

  5. 13. Applied bioinformatics for gene characterization

    Author : Raf M Podowski; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bioinformatics; gene characterization; text mining; data visualization;

    Abstract : As the vast majority of human protein-encoding genes are now identified, the new challenge placed before life scientists is the determination of the functions of the proteins. Traditionally, intense, directed efforts are applied to decipher the function of a novel protein using laboratory techniques. READ MORE

  6. 14. Genomics and bioinformatics approaches to functional gene annotation

    Author : Danielle Kemmer; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Biomedical research has been undergoing a quasi-revolution with the dawn of the genomics era. The flood of sequence data from the various genome projects, the task of cataloging the entire coding portion of a genome instead of identifying and characterizing individual genes, as well as technical demands accompanying these developments have posed great challenges to the research community. READ MORE

  7. 15. Disease activity, function and costs in early rheumatoid arthritis

    Author : Eva Hallert; Thomas Skogh; Jan Persson; Ronald van Vollenhoven; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Antirheumatic agents; Rheumatoid arthritis; Cost of illness; Health care costs; Joints physiopathology; Sex factors; Rheumatology; Reumatologi;

    Abstract : Rheumatoid arthritis (RA) is a major cause of progressive joint damage and disability, and is associated with decline in quality of life, reduced ability to work and increased health care utilisation. The economic consequences of the disease are substantial for the individuals and their families and for the society as a whole. READ MORE