Search for dissertations about: "Protein Transduction Domain"

Showing result 1 - 5 of 52 swedish dissertations containing the words Protein Transduction Domain.

  1. 1. Hormone-Sensitive Lipase and Protein Kinase B; Molecular characterization in testis, adipose tissue and pancreatic beta cells

    University dissertation from Section for Molecular Signalling, CMB, P.O. Box 94, S-221 00 Lund, Sweden

    Author : Lena Stenson; Lunds universitet.; Lund University.; [1998]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; pancreas; beta cells; adipocyte; insulin; Akt; protein kinase B; spermatogenesis; cholesterol esterase; hormone-sensitive lipase; testis; cAMP; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : Popular Abstract in Swedish Min avhandling är en s.k. sammanläggningsavhandling och innehåller fyra delarbeten (I-IV), vilka alla är publicerade i vetenskapliga tidskrifter. I delarbetena redovisas undersökningar av två enzymer, hormonkänsligt lipas (HKL) och proteinkinas B (PKB). READ MORE

  2. 2. Alpha-2 Adrenergic Receptors and Signal Transduction Effector Output in Relation to G-Protein Coupling and Signalling Cross-Talk

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Johnny Näsman; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; Adrenergic; receptor; G-protein; adenylyl cyclase; cAMP; calcium; cross-talk; Fysiologi och anatomi; MEDICINE Physiology and pharmacology; MEDICIN Fysiologi och farmakologi; Physiology; fysiologi;

    Abstract : The alpha-2 adrenergic receptor (α2-AR) subfamily includes three different subtypes, α2A-, α2B- and α2C-AR, all believed to exert their function through heterotrimeric Gi/o-proteins. The present study was undertaken in order to investigate subtype differences in terms of cellular response and to explore other potential signalling pathways of α2-ARs. READ MORE

  3. 3. The Tyrosine Kinase GTK Signal Transduction and Biological Function

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Cecilia Annerén; Uppsala universitet.; [2001]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; Protein tyrosine kinases; GTK; SHB; proliferation; survival; differentiation; β cells; pancreatectomy; cytokines; diabetes; PC12 cells; NGF; streptozotocin; focal adhesion kinase; RAP1; Cellbiologi; MEDICINE Morphology; cell biology; pathology Cell biology; MEDICIN Morfologi; cellbiologi; patologi Cellbiologi; medicinsk cellbiologi; Medical Cell Biology;

    Abstract : Protein tyrosine kinases play an important role in the regulation of various cellular processes such asgrowth, differentiation and survival. GTK, a novel SRC-like cytoplasmic tyrosine kinase, was recently cloned from a mouse insulinoma cell line and the present work was conducted in order to find a biological function of GTK in insulin producing and neuronal cells. READ MORE

  4. 4. Mechanisms of Integrin Signal Transduction

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Anne Stefansson; Uppsala universitet.; [2007]
    Keywords : Cell biology; Integrin; Integrin signalling; PI3K; Akt PKB; Integrin transmembrane domain; cell spreading; Cellbiologi;

    Abstract : Integrins are a protein family of cell surface receptors, expressed in all cell types in the human body, except the red blood cells. Besides their importance in mediating physical connections with the surrounding environment, the integrin family members are also vital signalling mediators. READ MORE

  5. 5. Signal Transduction by Proline-Rich Tyrosine Kinase Pyk2

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Inga Dikic; Uppsala universitet.; [2002]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi; Protein phosphorylation; tyrosine kinase; Pyk2 FAK; neuronal differentiation; Ras MAP kinase pathway; MEDICINE Surgery Oncology; MEDICIN Kirurgi Onkologi; molekylär cellbiologi; Molecular Cellbiology;

    Abstract : The proline-rich tyrosine kinase (Pyk2) together with focal adhesion kinase (FAK) define a family of non-receptor protein tyrosine kinases that are regulated by diverse stimuli. Activation of Pyk2 has been implicated in multiple signaling events, including modulation of ion channels, activation of MAP kinase cascades and apoptotic cell death. READ MORE