Search for dissertations about: "Protein alignment homology sequence profile"

Found 2 swedish dissertations containing the words Protein alignment homology sequence profile.

  2. 1. Sequence-based predictions of membrane-protein topology, homology and insertion

    Author : Andreas Bernsel; Gunnar von Heijne; Volkhard Helms; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; membrane protein; topology prediction; hidden markov model; homology detection; Sec translocon; Bioinformatics; Bioinformatik; Biochemistry; biokemi;

    Abstract : Membrane proteins comprise around 20-30% of a typical proteome and play crucial roles in a wide variety of biochemical pathways. Apart from their general biological significance, membrane proteins are of particular interest to the pharmaceutical industry, being targets for more than half of all available drugs. READ MORE

  4. 2. The use of evolutionary information in protein alignments and homology identification

    Author : Tomas Ohlson; Arne Elofsson; Sven Hovmöller; Geoffrey J. Barton; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein alignment homology sequence profile; Theoretical chemistry; Teoretisk kemi;

    Abstract : For the vast majority of proteins no experimental information about the three-dimensional structure is known, but only its sequence. Therefore, the easiest way to obtain some understanding of the structure and function of these proteins is by relating them to well studied proteins. This can be done by searching for homologous proteins. READ MORE