Search for dissertations about: "Protein modeling"

Showing result 6 - 10 of 182 swedish dissertations containing the words Protein modeling.

  2. 6. Bending, Twisting and Turning : Protein Modeling and Visualization from a Gauge-Invariance Viewpoint

    Author : Martin Lundgren; Antti Niemi; Jørgen Ellegaard Andersen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein folding; discrete frenet frame; solitons; protein visualization; Physics and Astronomy specializing in Theoretical Physics; Fysik och astronomi med inriktning mot teoretisk fysik;

    Abstract : Proteins in nature fold to one dominant native structure. Despite being a heavily studied field, predicting the native structure from the amino acid sequence and modeling the folding process can still be considered unsolved problems. In this thesis I present a new approach to this problem with methods borrowed from theoretical physics. READ MORE

  4. 7. Engineering yeast for improved recombinant protein production

    Author : Yanyan Wang; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; point mutation; genome-scale modeling; recombinant protein; omics analysis; CRISPR Cas9; protein secretion; Saccharomyces cerevisiae;

    Abstract : Recombinant proteins are broadly used from basic research to therapeutic development and include industrial enzymes and pharmaceutical proteins. The increasing demand for improved production and enhanced quality of recombinant proteins requires robust biotech-based strategies to overcome the limitations of protein extraction from natural sources. READ MORE

  5. 8. Protein Structure Prediction : Model Building and Quality Assessment

    Author : Björn Wallner; Arne Elofsson; Michael Levitt; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein structure prediction; proteinstrukturförutsägelse; Bioinformatics; Bioinformatik;

    Abstract : Proteins play a crucial roll in all biological processes. The wide range of protein functions is made possible through the many different conformations that the protein chain can adopt. The structure of a protein is extremely important for its function, but to determine the structure of protein experimentally is both difficult and time consuming. READ MORE

  6. 9. Modeling of Protein Folding and Genetic Networks

    Author : Fredrik Sjunnesson; Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Matematisk och allmän teoretisk fysik; thermodynamics; two-state folding; Protein folding; all-atom model; Mathematical and general theoretical physics; Kauffman model.; local update; Monte Carlo; classical mechanics; quantum mechanics; relativity; statistical physics; gravitation; klassisk mekanik; kvantmekanik; relativitet; statistisk fysik; termodynamik; Fysicumarkivet A:2003:Sjunnesson;

    Abstract : Models for potein folding are developed and applied to peptides and small proteins with both α-helix and β-sheet structure. The energy functions, in which effective hydrophobicity forces and hydrogen bonds are taken to be the two central terms, are sequence-based and deliberately kept simple. READ MORE

  7. 10. Modeling of Hindered Diffusion in Gels

    Author : Jan Gutenwik; Avdelningen för kemiteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; effective diffusion coefficient; pore size distribution; obstruction; immobilization; modeling; adsorption kinetics; hindered diffusion; simulation program; proteins; Chemical technology and engineering; Kemiteknik och kemisk teknologi;

    Abstract : Hindered diffusion occurs in the most different processes, as has been described in this thesis. It is very important to have an understanding of the influence of hindered diffusion on the mass transfer rate, especially when competing rate processes are acting simultaneously. READ MORE