Search for dissertations about: "Protein"

Showing result 41 - 45 of 8563 swedish dissertations containing the word Protein.

  2. 41. Protein folding studies of human superoxide dismutase and ALS associated mutants

    Author : Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

    Abstract : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. READ MORE

  4. 42. Systems biology of protein synthesis and secretion in yeast

    Author : Qi Qi; Chalmers tekniska högskola; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; recombinant protein production; protein synthesis; multi-omics analysis; protein secretion; genome-scale modeling;

    Abstract : Protein synthesis and secretion is a vital process to maintain cell function. As it demands numerous building blocks, cofactors and chaperones generated from metabolism and translation, the process is intertwined with metabolic and regulatory networks. READ MORE

  5. 43. Biophysical characterization of protein-protein interactions involving intrinsically disordered proteins

    Author : Ida Nyqvist; Jakob Dogan; Ivarsson Ylva; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Intrinsically disordered proteins; Protein-protein interactions; Disorder-to-order transition; Rate-limiting transition state; Ф-value analysis; NMR relaxation; Side-chain dynamics; Backbone dynamics; Conformational entropy change; Biophysics; biofysik;

    Abstract : Intrinsically disordered proteins and regions (IDPs/Rs) are proteins that do not form stable and well-defined structures in their free states but rather occupy an ensemble of conformations that change over time while still staying functional. They are prevalent in the eukaryotic proteome and are involved in various vital processes in the cell where they often interact with their binding partners through coupled binding and folding reactions. READ MORE

  6. 44. An evolutionary basis for protein design and structure prediction

    Author : Christoffer Norn; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Protein evolution; Biophysics; Protein design; Protein structure prediction;

    Abstract : The sequence diversity of protein families is a result of the biophysical selection pressures that shaped their evolutionary history. Among the dominant pressures is selection for protein thermostability, which in itself is an attractive target in protein engineering because of its importance for various biopharmaceutical properties, the performance of industrial enzymes, and the ability to design new protein functions. READ MORE

  7. 45. Protein Interactions Involving the Laminin G-type Domains of Vitamin K-dependent Protein S

    Author : Petra Evenäs; Malmö Klinisk kemi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Klinisk kemi; Clinical chemistry; tyrosine phosphorylation.; Sky receptor; SHBG-like region; protein S; G domain; Gas6; Activated protein C; C4b-binding protein; Proteins; enzymology; Proteiner; enzymologi;

    Abstract : The studies described in this thesis focus on the involvement of the two laminin G-type domains of vitamin K-dependent protein S in various biological contexts. The G-type domains are located in the C-terminal sex-hormone-binding globulin (SHBG)-like region. READ MORE