Search for dissertations about: "Proteome"

Showing result 1 - 5 of 198 swedish dissertations containing the word Proteome.

  1. 1. The Membrane Proteome Evolution, Characteristics and Classification

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Markus Sällman Almén; Uppsala universitet.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane proteins; Membrane proteome; molecular evolution; GPCRs; Dispanins; IFITM; Medicinsk vetenskap; Medical Science;

    Abstract : Membrane proteins are found in all kingdoms of life and are essential for cellular interactions with the environment. Although a large research effort have been put into this group many membrane proteins remains uncharacterized, both in terms of function and evolutionary history. READ MORE

  2. 2. Mapping the human proteome using bioinformatic methods

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Linn Fagerberg; KTH.; [2011]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; proteome; transcriptome; bioinformatics; membrane protein prediction; subcellular localization; protein expression level; cell line; immunohistochemistry; immunofluorescence; NATURAL SCIENCES Biology Other biology Bioinformatics; NATURVETENSKAP Biologi Övrig biologi Bioinformatik; SRA - Molekylär biovetenskap; SRA - Molecular Bioscience;

    Abstract : The fundamental goal of proteomics is to gain an understanding of the expression and function of the proteome on the level of individual proteins, on the level of defined cell types and on the level of the entire organism. In this thesis, the human proteome is explored using membrane protein topology prediction methods to define the human membrane proteome and by global protein expression profiling, which relies on a complex study of the location and expression levels of proteins in tissues and cells. READ MORE

  3. 3. Proteome wide protein production

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Hanna Tegel; KTH.; [2013]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; protein production; Escherichia coli; transcription; promoter; translation; rare codon; high-throughput; screening;

    Abstract : Over a decade after the completion of the human genome, researchers around the world are still wondering what information is hidden in the genome. Although the sequences of all human genes are known, it is still almost impossible to determine much more than the primary protein structure from the coding sequence of a gene. READ MORE

  4. 4. Profiling the cancer proteome

    University dissertation from Department of Immunotechnology, Lund University

    Author : Sofia Waldemarson; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytologi; onkologi; cancer; Biotechnology; Bioteknik; cancerology; oncology; Cytology; iTRAQ; biomarkers; DIGE; two-dimensional gel electrophoresis; Proteomics;

    Abstract : Popular Abstract in Swedish Cancer är en komplex och heterogen sjukdom där celler har börjat växa okontrollerat och denna sjukdom är idag ett stort hälsoproblem. På grund av diffusa symptom upptäcks cancern ofta i ett sent stadium. READ MORE

  5. 5. Antibody-based subcellular localization of the human proteome

    University dissertation from Stockholm : KTH Royal Institute of Technology

    Author : Marie Skogs; KTH.; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Human proteome; Subcellular localization; Organelles; Immunofluorescence; Fixation; Permeabilization; Antibody validation; Biotechnology; Bioteknologi;

    Abstract : This thesis describes the use of antibodies and immunofluorescence for subcellular localization of proteins. The key objective is the creation of an open-source atlas with information on the subcellular location of every human protein. READ MORE