Search for dissertations about: "Psoriasin"

Showing result 1 - 5 of 7 swedish dissertations containing the word Psoriasin.

  2. 1. Functional genetic studies of Psoriasin: a potential biomarker for breast cancer with a poor prognosis

    Author : Stina Petersson; Göteborgs universitet; []
    Keywords : Psoriasin; Breast cancer; Reactive oxidant species; NF-κB; IFNγ; STAT1; ICAM-1; MUC1; CD24;

    Abstract : Breast cancer is the most common malignancy in women. There is a high degree of heterogeneity in breast tumours and they can be divided into subtypes that have different expression pattern and clinical outcome. Ductal Carcinoma in situ (DCIS) is regarded as a precursor of invasive ductal breast cancer. READ MORE

  4. 2. Psoriasin For Better or for Worse in Sickness and in Health : The Role of Psoriasin in Angiogenesis and Differentation of Epithelial Cells

    Author : Jenny Vegfors; Charlotta Enerbäck; Anna-Karin Ekman; Maria Carlström; Ingemar Rundquist; Enikö Pivarcsi Sonkoly; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Psoriasin (S100A7), a member of the S100 family of calcium-binding proteins, is highly expressed in high-grade ductal carcinoma in situ (DCIS) and in the benign hyper-proliferative skin disorder psoriasis. Both breast cancer and psoriasis are diseases which are characterized by hyperproliferation and a disturbed differentiation of the epithelial cells as well as a pronounced angiogenesis. READ MORE

  5. 3. ANALYSIS OF NOVEL BIOMARKERS FOR UNFAVORABLE BREAST CANCER PROGNOSIS

    Author : Emman Shubbar; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ductal Carcinoma In Situ DCIS ; Primary invasive breast cancer; Biomarkers;

    Abstract : Breast cancer is the most common malignancy in women, and a major cause of mortality and morbidity despite the advances in diagnosis and treatment. The main challenge remains to identify novel biomarkers in order to improve existing treatment modalities. Ductal carcinoma in situ (DCIS) is considered as a direct precursor of invasive breast cancer. READ MORE

  6. 4. Innate immune factors in recurrent and persistent infections of the lower female genital tract

    Author : Cathrin Alvendal; Karolinska Institutet; Karolinska Institutet; []
    Keywords : C. albicans;

    Abstract : Background: Infections of the female genital tract are common and have severe impact on the quality of life and sexual health of affected women. The innate immune system is crucial and is involved in the defense of infections. READ MORE

  7. 5. Diagnostic and prognostic markers in primarily non-smoking related head and neck cancer

    Author : Mark Zupancic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Head and neck cancer (HNC) includes cancers of the oral cavity, the pharynx (i.e., the nasopharynx, the oropharynx, and the hypopharynx), the larynx, the nasal cavity, the paranasal sinuses, and the salivary glands. READ MORE