Search for dissertations about: "PtP"
Showing result 1 - 5 of 25 swedish dissertations containing the word PtP.
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1. Aperiodic Array Synthesis for Telecommunications
Abstract : Arrays of antennas offer important advantages over single-element antennas and are thus a key part of most advanced communication systems. The majority of current arrays are based on a classical regular layout, which offer simple design criteria despite some limitations. READ MORE
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2. Molecular Regulation of Angiogenesis
Abstract : Angiogenesis, de novo formation of blood vessels from the pre-existing vasculature, is crucial in embryo development, and in processes in the adult such as wound healing and ovulation. Angiogenesis is also involved in pathological conditions such as cancer and chronic inflammatory diseases, which are propagated by dysregulated, excess angiogenesis. READ MORE
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3. T-Cell Protein Tyrosine Phosphatase, a Regulator of the PDGF Signaling Pathway
Abstract : Platelet-derived growth factor (PDGF) is a potent stimulator of cell growth, survival and motility. PDGF exerts its function by binding to specific tyrosine kinase receptors, initiating receptor auotphosphorylation and initiation of specific signaling pathways that regulates the cellular response. READ MORE
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4. Regulation of PDGFRβ signaling
Abstract : Platelet-derived growth factor (PDGF) isoforms, which bind to closely related a- and b-tyrosine kinase receptors, induce migration, proliferation, survival and differentiation of mesenchymal cells. They signal by the active receptor attracting Src homology 2 (SH2) domain containing proteins, which subsequently initiate a set of signaling pathways. READ MORE
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5. Regulation of Platelet-Derived Growth Factor Receptor Signaling and its Targeting in Cancer Therapy
Abstract : Overactivity of platelet-derived growth factor receptor (PDGFR) is a frequent event in many types of solid tumors. Therefore, it is of great importance to uncover the mechanisms that regulate PDGF/PDGFR signalling, to develop efficient inhibitors targeting this pathway. READ MORE