Search for dissertations about: "Pulmonary"
Showing result 1 - 5 of 755 swedish dissertations containing the word Pulmonary.
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1. Pulmonary Drug Absorption : In vitro and in vivo investigations of drug absorption across the lung barrier and its relation to drug physicochemical properties
Abstract : Although, pulmonary drug delivery is a well established means for targeting of drugs to the lungs for the treatment of respiratory diseases as well as for the systemic delivery of volatile anesthetic agents, drug absorption kinetics in the lung have not been subjected to extensive research. The main objective of this thesis was to investigate drug absorption characteristics of the lung barrier, using the isolated and perfused rat lung model and in vivo pharmacokinetic studies in rats. READ MORE
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2. Acute Pulmonary Embolism : not just an acute condition after all
Abstract : Background: Acute pulmonary embolism (PE) is the third most common cardiovascular disease following myocardial infarction and stroke. Despite diagnostic improvements, the diagnosis of PE is still associated with many difficulties, as the symptoms of an acute PE are nonspecific. READ MORE
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3. Pulmonary hypertension. Clinical and pathophysiological studies
Abstract : Pulmonary hypertension (PH) is a common abnormality, most often associated with various cardiopulmonary diseases. Pulmonary arterial hypertension (PAH) is a devastating pulmonary vascular disease characterised by the proliferation of endothelial, smooth-muscle cells and fibroblasts. READ MORE
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4. Obstructive pulmonary disease : Studies of acute exacerbations and immunologic status
Abstract : In this thesis, different aspects of the treatment and care of patients with asthma and chronic obstructive pulmonary disease (COPD) have been studied.In a study of 50 patients seeking medical care for an acute exacerbation of asthma or COPD, we studied inflammatory markers in blood, sputum and urine. READ MORE
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5. Pulmonary Atelectasis in General Anaesthesia : Clinical Studies on the Counteracting Effects of Positive End-Expiratory Pressure
Abstract : Partial lung collapse, i.e., pulmonary atelectasis, is common during general anaesthesia. The main causal mechanism is reduced lung volume with airway closure and subsequent gas absorption from preoxygenated alveoli. READ MORE