Search for dissertations about: "Purple acid phosphatase"

Showing result 1 - 5 of 6 swedish dissertations containing the words Purple acid phosphatase.

2. 1. Regulation of tartrate-resistant purple acid phosphatase by proteolytic processing in rat

   Author : Jenny Ljusberg-Sjölander; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Purple acid phosphatase; enzyme catalysis; proteolytic processing;

   Abstract : Purple acid phosphatase (PAP) is an iron-containing binuclear acid metallohydrolase with a characteristic purple colour, also referred to as tartrate-resistant acid phosphatase (TRAP), uteroferrin or type 5 acid phosphatase. PAP is highly expressed in osteoclasts and has a role in bone resorption. READ MORE

4. 2. Structural studies of saccharopine reductase and purple acid phosphatase

   Author : Eva Johansson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Lysine is synthesised in two different ways in living organisms, either by the diaminopimelate pathway or the [alpha]-aminoadipate pathway. These routes belong to the aspartate and the glutamate family of amino acid biosynthesis, respectively. READ MORE

5. 3. Expression and post-translational modification of purple acid phosphatase in insect and mammalian cells

   Author : Yunling Wang; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Purple acid phosphatase (PAP) is an acidic metallohydrolase that contain a binuclear iron center in its active site. In mammals, this enzyme is also referred to as tartrate-resistant acid phosphatase (TRAPs), uteroferrin or type 5 acid phosphatase. READ MORE

6. 4. Tartrate resistant acid phosphatase in the immune and nervous system : distribution and pathophysiological implications

   Author : Pernilla Lång; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Tartrate resistant acid phosphatase (TRAP) belongs to the family of purple acid phosphatases (PAP). It is a glycoprotein synthesized as a monomer with low enzyme activity containing a redox active diiron centre in the active site. Post-translational proteolytic processing of this monomer into a dimeric protein increases the enzyme activity. READ MORE

7. 5. Biogenesis of tartrate-resistant acid phosphatase isoforms 5a and 5b in cell and animal models

   Author : Serhan Zenger; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Tartrate-resistant acid phosphatase (TRAP) is an iron-containing binuclear acid metallohydrolase that belongs to the purple acid phosphatase (PAP) family. It is a glycoprotein translated as a monomeric protein but is commonly isolated from tissues as a proteolytically processed dimeric form with increased enzyme activity. READ MORE