Search for dissertations about: "Q locus"

Showing result 1 - 5 of 16 swedish dissertations containing the words Q locus.

  2. 1. The Complex Genetics of Mouse Reproduction and Arhritis

    Author : Maria Liljander; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; morula; B10.Q mice; genetics.; Pregnancy; CIA; reproduction; QTL; superovulation; blastocysts; oocytes; litter size; RA; NFR N mice; MHC;

    Abstract : ABSTRACT Optimal breeding of mice is very important in biomedical science today. The understanding why some strains breed better and some worse enable scientists to create better in vivo models for human diseases. READ MORE

  4. 2. EBV gene variation and epigenetic alterations in asian nasopharyngeal carcinoma and potential clinical applications

    Author : Do Nguyen-Van; Karolinska Institutet; Karolinska Institutet; []
    Keywords : EBV; EBNA1; LMP1; LMP2A; FR; Q locus; genetic variation; antisense oligonucleotide; CDH13; DNA methylation; epigenetics; nasopharyngeal carcinoma;

    Abstract : The incidence of nasopharyngeal carcinoma (NPC), an epithelial tumor, varies remarkably in different geographic regions and human populations. The Epstein-Barr virus (EBV), other environmental factors and genetic susceptibility are all considered to be involved in the etiology of this form of cancer and the EBV has been extensively studied in this context. READ MORE

  5. 3. Characterization of human chromosome 22 : cloning of breakpoints of the constitutional translocation t(11;22)(q23;q11) and detection of small constitutional delections by microarray CGH

    Author : Isabel Tapia Paez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chromosome 22; t 11; 22 q23; q 11 ; inverted repeats palindromes; DiGeorge Velo-cardio-facial syndrome; array-CGH;

    Abstract : Chromosome 22 is the second smallest human chromosome, composing approximately 1.5% of the genome. The short arm of this acrocentric chromosome harbors ribosomal genes and the long arm contains the protein coding genes. READ MORE

  6. 4. T cells, Cytokines, and Genetic Factors in Autoimmunity Studies of experimental models of arthritis and sialadenitis

    Author : Åsa Johansson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; Collagen-induced arthritis Sialadenitis Mice Knockout Linkage analysis T cells Cytokines; muscle system; Skeleton; reumatologi; muskelsystem; Skelett;

    Abstract : To understand the pathogenesis of autoimmune diseases we have to consider the problem from different angles. Animal models provide a tool to further understand these complex diseases, as the influence of genetic and environmental factors could be limited. READ MORE

  7. 5. Looking for arthritis regulating genes on mouse chromosome 6 & 14

    Author : Marjan Popovic; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease of the joints with a complex aetiology affected by largely unknown genetic and environmental factors. Since ~60% of susceptibility to RA is genetically inherited, one way to progress towards understanding of the disease is to identify the disease regulating genes. READ MORE