Search for dissertations about: "Q10"

Showing result 1 - 5 of 12 swedish dissertations containing the word Q10.

  2. 1. Influence of Oxidative Stress on Muscle and Bone

    Author : Bengt Östman; Karl Michaëlsson; Lars Nordsletten; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bone mineral density; coenzyme Q10; exercise; ischaemia; isprostanes; muscle; oxidative stress; oxygen radicals; reperfusion; tocopherol; Orthopaedics; Ortopedi; ortopedi; Orthopaedics;

    Abstract : Reactive oxygen species (ROS) induce oxidative stress and although are primarily recognized for playing a deleterious biological role, they can be beneficial to cell systems. ROS are extremely short-lived and normally tightly regulated by antioxidant defence systems. READ MORE

  4. 2. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy

    Author : Malou Friederich Persson; Fredrik Palm; Richard K. Porter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; mitochondria; Uncoupling Protein-2; Adenosine Nucleotide Transporter; uncoupling; diabetes; diabetic nephropathy; db db; dinitrophenol; Coenzyme Q10; oxygen; rats; mice; Physiology; Fysiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. READ MORE

  5. 3. Endogenous antioxidants in human skeletal muscle and adaption in energy metabolism : with reference to exercise-training, exercise-related factors and nutrition

    Author : Michael B Svensson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : GSH; urate; Q10; Ubiquinone-10; myoblasts; muscle stem cells; high-intensity exercise; performance; overload training; adenine nucleotides; AMP deaminase; glycogen; carbohydrates.;

    Abstract : The antioxidant homeostasis is determined by a wide array of interacting cellular antioxidants, as well as being influenced by the homeostasis in energy metabolism. Changes in antioxidant homeostasis, as a consequences of altered production of reactive oxygen species (ROS). and/or by changes in the resident levels of antioxidants. READ MORE

  6. 4. Effects of Ubiquinone-10 on the Stability and Mechanical Properties of Lipid Membranes

    Author : Emma K. Eriksson; Katarina Edwards; Victor Agmo Hernández; Emma Sparr; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; ubiquinone-10; lipid bilayers; membrane stabilizer; liposome permeability; osmotic shock; cuvettes; solanesol; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

    Abstract : Ubiquinones are a group of fat-soluble molecules present in many biological membranes. The most abundant version in humans, ubiquinone-10 (Q10), plays an important role in the mitochondrial respiration chain and also functions as a powerful antioxidant. Accumulating evidence suggests that Q10 also could have other functions in the membrane. READ MORE

  7. 5. Post-polio syndrome : physiotherapeutic analysis and interventions

    Author : Katarina Skough; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Post-polio syndrome;

    Abstract : This thesis presents four studies focusing on outcomes of gait performance using gait analysis and/or the Six-minute-walk test (6MWT), in patients with post-polio syndrome (PPS). Further, resistance training in combination with Coenzyme Q10 (Q10) and intravenous immunoglobulin treatment (IvIg) in PPS patients was evaluated. READ MORE