Search for dissertations about: "Quantitative genetics"

Showing result 1 - 5 of 124 swedish dissertations containing the words Quantitative genetics.

  1. 1. Novel Statistical Methods in Quantitative Genetics Modeling Genetic Variance for Quantitative Trait Loci Mapping and Genomic Evaluation

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Xia Shen; Uppsala universitet.; Högskolan Dalarna.; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; statistical genetics; quantitative trait loci; genome-wide association study; genomic selection; genetic variance; hierarchical generalized linear model; linear mixed model; random effect; heteroscedastic effects model; variance-controlling genes; Komplexa system - mikrodataanalys;

    Abstract : This thesis develops and evaluates statistical methods for different types of genetic analyses, including quantitative trait loci (QTL) analysis, genome-wide association study (GWAS), and genomic evaluation. The main contribution of the thesis is to provide novel insights in modeling genetic variance, especially via random effects models. READ MORE

  2. 2. Type 2 Diabetes Genes Contributing to Insulin Secretion Defects

    University dissertation from Department of Clinical Sciences, Lund University

    Author : Charlotte Granhall; Lunds universitet.; Lund University.; [2007]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sekretion; Endokrinologi; exocytosis; GK rat; NIDDM1I; genetics; gene expression; quantitative trait analysis; Sorcs1; Adra2a; Endocrinology; diabetology; insulin secretion; diabetologi; secreting systems; Type 2 diabetes;

    Abstract : Type 2 diabetes is caused by a combination of environmental and inherited factors influencing the progression of insulin resistance and impaired insulin secretion leading to chronically elevated blood glucose levels. The aim of this thesis was to functionally and genetically characterise the species-conserved diabetes locus Niddm1i of the GK rat encoding hyperglycaemia and defect insulin secretion. READ MORE

  3. 3. Domestication Effects on the Stress Response in Chickens Genetics, Physiology, and Behaviour

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Amir Fallahshahroudi; Linköpings universitet.; Linköpings universitet.; [2017]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Animal domestication; stress response; gene expression; QTL; eQTL;

    Abstract : Animal domestication, the process where animals become adapted to living in proximity to humans, is associated with the alteration of multiple traits, including decreased fearfulness and stress response. With an estimated population of 50 billion, the domesticated chicken is the most populous avian species in the world. READ MORE

  4. 4. Genetic Analysis of Quantitative Traits Using Domestic Animals A Candidate Gene and Genome Scanning Approach

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Hee-Bok Park; Uppsala universitet.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Domestication; horse; pig; chicken; quantitative traits; candidate gene; genome scan; PRKAG3; MC4R; selection experiment; growth; correlated response; metabolic disorders; Quantitative Trait Loci; linkage; single nucleotide polymorphisms; Genetik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik;

    Abstract : Domestication has led to genetic changes that affect quantitative traits in farm animals. Both candidate gene analysis using association tests and genome scans based on linkage analysis have been performed to understand the molecular basis underlying quantitative genetic variation in horses, pigs and chickens. READ MORE

  5. 5. Quantitative genetics of Norway spruce in Sweden

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : DefaultFirstname DefaultLastName; Sveriges lantbruksuniversitet.; [2016]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Abstract : Genetic improvement of solid wood and pulp and paper products related wood quality traits are important to increase productivity and value of Norway spruce plantation in Sweden. To incorporate wood quality traits into Norway spruce tree breeding program, genetic parameters of solid wood and fibre traits were investigated in a large Norway spruce population. READ MORE