Search for dissertations about: "Quantitative trait loci QTL"

Showing result 16 - 20 of 61 swedish dissertations containing the words Quantitative trait loci QTL.

  2. 16. The Complex Genetics behind Neurodegeneration and Susceptibility to Parkinson’s disease

    Author : Michael Jewett; Translationell Neurogenetik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s Disease; α-synuclein; Dopaminergic Neurons; Susceptibility; GSTA4; Vra1; rAAV; 6-OHDA; En1; Linkage analysis; Congenic strains; Axonal swellings; QTL; Risk factors; Neuroprotection; Astrocytes;

    Abstract : Parkinson’s disease (PD) is the second most common neurodegenerative disorder and affects over 1% of people above the age of 65. This progressive and debilitating disease is usually thought of as a motor disease, with symptoms such as muscle rigidity, slowness of movement, and tremor at rest. READ MORE

  4. 17. Identification of Arthritis Susceptibility Genes in Mice and Humans

    Author : Emma Ahlqvist; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunologi; transplantation; serology; Immunology; Medicin människa och djur ; Medicine human and vertebrates ; Biomedicinska vetenskaper; QTL; Biomedical sciences; Rheumatoid arthritis; Collagen-induced arthritis; serologi; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi; Clinical genetics; Klinisk genetik;

    Abstract : Rheumatoid arthritis (RA) is a chronic autoimmune disease with a largely unknown aetiology. The risk of developing RA is partly dependent on genetic factors, which has motivated extensive efforts to identify the disease regulating genes as away to understand disease pathogenesis. READ MORE

  5. 18. Numerical methods for mapping of multiple QTL

    Author : Kajsa Ljungberg; Sverker Holmgren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Beräkningsvetenskap; Scientific Computing;

    Abstract : This thesis concerns numerical methods for mapping of multiple quantitative trait loci, QTL. Interactions between multiple genetic loci influencing important traits, such as growth rate in farm animals and predisposition to cancer in humans, make it necessary to search for several QTL simultaneously. READ MORE

  6. 19. Genetic Analysis of Fat Metabolism in Domestic Pigs and their Wild Ancestor

    Author : Frida Berg; Leif Andersson; Maria Moller; Stefan Marklund; Sigbjörn Lien; Uppsala universitet; []
    Keywords : Genetics; Pig; Quantitative Trait Locus; Fat deposition; FAT1; Linkage map; RH map; Comparative map; Backcross; Identical by Descent mapping; Brown adipose tissue; UCP1; Genetik;

    Abstract : The domestication of the pig began about 9 000 years ago and many of the existing domestic breeds have been selected for phenotypic traits like lean meat and fast growth. Domestic pigs are phenotypically very different from the ancestral wild boar that has adapted to survive in their natural environment. READ MORE

  7. 20. Exploring Coagulation Properties in Bovine Milk Using Milk Genomics Approaches

    Author : Frida Gustavsson; Livsmedelsteknik; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Bovine milk; rennet-induced gelation; milk genomics; Swedish Red dairy cattle; milk composition; technological properties; cheese; genetic polymorphism; quantitative trait locus; protein profile; casein micelle; calcium content;

    Abstract : Swedish Red (SR) dairy cattle is the second most common breed in Sweden and hence SR milk quality is crucial for the nutritional value and the processability of the milk delivered to the Swedish dairies. This thesis will give an insight into the quality of milk from SR cows and it will illuminate the possibilities for improvements of both breeding programs and the quality of different dairy products, focusing on cheese characteristics. READ MORE