Search for dissertations about: "Quinolone"
Showing result 1 - 5 of 22 swedish dissertations containing the word Quinolone.
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1. Pharmacophore Refinement and Lead Optimization - A study of the benzodiazepine site of the GABAA receptors
Abstract : Structure activity relationship studies of synthetic flavone derivatives have been utilized to refine and evaluate a pharmacophore model of the benzodiazepine binding site of the GABAA receptors, originally developed by Zhang et al. (Drug Des. Discovery 1995, 12, 193-248). READ MORE
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2. Quinolone resistance in Bacteroides fragilis and Pseudomonas aeruginosa, two opportunistic pathogens
Abstract : Opportunistic pathogens can cause infections in case of structural or functional defects in the host. Examples of Gram-negative opportunists are the Bacteroides fragilis group, anaerobic, non-spore forming rods and the aerobic, non-fermentative rod Pseudomonas aeruginosa. READ MORE
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3. Molecular mechanisms of fluoroquinolone resistance in Pseudomonas aeruginosa
Abstract : Pseudomonas aeruginosa is an opportunistic nosocomial pathogen. In compromised human, it can cause infections in urinary tract, wound and respiratory tract such as pneumonia and progressive lung diseases. READ MORE
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4. Design and synthesis of steroid mimetic libraries using solid phase techniques
Abstract : This thesis deals with the design and synthesis of biologically active ligands for nuclear hormone receptors using combinatorial techniques. In the first part, a 5,6,6a,7,8,9,10,10a-octahydrobenzo[f]quinolin-3(4H)-one tricyclic core structure was designed mimicking the ABC-rings of a steroid. READ MORE
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5. Antimicrobial resistant Escherichia coli in faeces from preweaned dairy calves : prevalence, risk factors, and spread
Abstract : Antimicrobial resistant (AMR) bacteria are increasing threats for human and veterinary medicine. Faecal Escherichia coli (E. coli) from preweaned dairy calves is often resistant to multiple antimicrobials and calves may therefore serve as reservoirs for these bacteria and their resistance genes. READ MORE