Search for dissertations about: "RA"
Showing result 16 - 20 of 508 swedish dissertations containing the word RA.
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16. Regulation of human mast cell development
Abstract : Mast cells are multifunctional effector cells of the immune system and are best known for theirparticipation in allergic reactions. The aim of this thesis was to investigate how the stem cell factor(SCF)-dependent development of mast cells from cord blood can be regulated by different factors, and tostudy how immature mast cells circulating in the blood can be recruited into the tissue. READ MORE
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17. Early development of the olfactory placode and early rostrocaudal patterning of the caudal neural tube
Abstract : The development of the nervous system is a complex process. Cell divisions, cell differentiation and signalling interactions must be tightly regulated. To comprehend the mature nervous system, we have to understand its assembly during development. READ MORE
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18. The impact of autoimmune thyroid disease (AITD) on rheumatoid arthritis (RA) and the impact of RA on AITD
Abstract : Study I. Background: The Swedish National Patient Register (NPR) is a unique source for the identification of large cohorts of rheumatoid arthritis (RA) patients. The general validity of this register has been reported to be high. READ MORE
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19. Rho-GTPases in Rheumatoid Arthritis
Abstract : The success of alleviating rheumatoid arthritis (RA) symptoms is complicated by both heterogeneity of the disease and lack of predictive markers to guide treatment options. Deregulated Rho-GTPases, a family of hydrolase enzymes catalyzing guanosine triphospate (GTP) to guanosine diphospate (GDP), have a detrimental role in many diseases including RA. READ MORE
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20. Induction and repair of clustered DNA damage sites after exposure to ionizing radiation
Abstract : The mechanisms that maintain genomic stability safeguard cells from constant DNA damage produced by endogenous and external stressors. Therefore, this thesis aimed to specifically address questions regarding the requirement and involvement of DNA repair proteins in the repair of various types of radiation-induced DNA damage. READ MORE