Search for dissertations about: "RAS"
Showing result 16 - 20 of 200 swedish dissertations containing the word RAS.
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16. Numerical Modelling of Timber Building Components to Prevent Disproportionate Collapse
Abstract : An increasing number of multi-storey buildings are being constructed with engineered wood products, such as glulam or cross-laminated timber (CLT). Multi-storey timber buildings can be safely designed for foreseeable loads, but knowledge is limited concerning their ability to survive unforeseeable events, e.g. READ MORE
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17. Molecular Mechanisms in Endothelial Cell Differentiation
Abstract : Angiogenesis is the formation of new blood vessels from the pre-existing blood vessels. Blood vessels are composed of endothelial cells and supporting musculature. Angiogenesis is regulated by numerous soluble ligands and by cell-matrix interactions. READ MORE
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18. Cellular targets of Pseudomonas aeruginosa toxin Exoenzyme S
Abstract : Pseudomonas aeruginosa is an opportunistic pathogen that can cause life-threatening infections in immunocompromised patients. It uses a type III secretion dependent mechanism to translocate toxic effector proteins directly into the eukaryotic cell. READ MORE
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19. Cell signaling by Rho and Miro GTPases : Studies of Rho GTPases in Cytoskeletal Reorganizations and of Miro GTPases in Mitochondrial Dynamics
Abstract : The Ras superfamily of GTPases embraces six major branches of proteins: the Ras, Rab, Ran, Arf, Rho and Miro subfamilies. The majority of GTPases function as binary switches that cycle between active GTP-bound and inactive GDP-bound states. This thesis will focus primarily on the biological functions of the Rho and Miro proteins. READ MORE
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20. Cellular targets of HAMLET, their role in tumor cell death and therapeutic potential
Abstract : Protein-lipid complexes have broad and specific effects against cancers of different origins. HAMLET (Human Alpha-lactalbumin Made LEthal to Tumor cells) is a complex of partially unfolded α-lactalbumin and oleic acid that kills a wide range of tumor cells but leaves healthy differentiated cells unaffected. READ MORE