Search for dissertations about: "RBCs"

Showing result 1 - 5 of 38 swedish dissertations containing the word RBCs.

  2. 1. Studies on Plasmodium falciparum asexual blood stage antigens : RAP-2/RSP-2 and Pf332 in focus

    Author : Nancy Awah; Klavs Berzins; Marcel Hommel; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunity; malaria; RBCs; anaemia; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The life cycle of the malaria parasite is very complex and provides a number of potential targets for vaccination. In this thesis, data on two plasmodial asexual blood stage antigens (RAP-2 and Pf332) are presented. READ MORE

  4. 2. Towards a detailed understanding of the red blood cell storage lesion : and its consequences for in vivo survival following transfusion

    Author : Andreas Hult; Christer Malm; Per-Arne Oldenborg; Martin L. Olsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Red blood cell; erythrocyte; transfusion; macrophage; phagocytosis; storage lesion; eryptosis; Class A scavenger receptor; transfusion medicine; transfusionsmedicin;

    Abstract : Red blood cells (RBCs) are vital for oxygen delivery to tissues and constitute the vast majority of all cells in blood. After leaving the red bone marrow as mature cells, RBCs have a lifespan of approximately 120 days before they are removed from the circulation by macrophages, mainly in the spleen and liver. READ MORE

  5. 3. The role of red blood cells in inflammation and remodeling

    Author : Karin Fredriksson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Red blood cells; fibroblast; inflammation; remodeling; fibrosis;

    Abstract : Besides being carriers of oxygen and carbon dioxide, red blood cells (RBCs) also have a scavenger function, binding inflammatory mediators to surface receptors. Animal and experimental models have suggested a role for RBCs in inflammatory and fibrotic responses and patients with idiopathic pulmonary hemosiderosis, a disease characterized by lung hemorrhage, frequently develop fibrosis. READ MORE

  6. 4. The role of red blood cells in cardiac and endothelial dysfunction in cardiometabolic disease

    Author : Tong Jiao; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Background: Cardiometabolic disease, which includes the combination of cardiovascular disease, especially coronary artery disease and type 2 diabetes (T2D), is a major health problem and cause of mortality worldwide. ST-elevation myocardial infarction (STEMI) occurs when coronary arteries are occluded and is regarded as a life-threatening disorder. READ MORE

  7. 5. Role of the CD47/SIRPα-interaction in regulation of macrophage phagocytosis

    Author : Mattias Olsson; Per-Arne Oldenborg; Hans Tapper; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; immunology; cell biology; Histology; Histologi;

    Abstract : CD47 is a cell surface glycoprotein that is expressed by virtually all cells in the body. Binding of CD47 to the macrophage receptor Signal Regulatory Protein alpha (SIRPα) yields an inhibitory signal that counteracts phagocytosis. READ MORE